Results 111 to 120 of about 4,099,878 (253)

Bayesian sequential estimation of the proportion of damage in maize seeds

Scientia Agricola
Sampling is an essential step in estimating a parameter: thus, cost and time associated to this step should be minimized. Sequential sampling is characterized by using samples of variable sizes given as a function of observations, and sequential sampling
Isabela da Silva Lima, Carla Regina Guimarães Brighenti, Raquel Maria de Oliveira Pires   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

IMAGE SEGMENTATION USING GAUSSIAN MIXTURE MODEL

International Journal of Industrial Engineering and Production Research, 2008
Stochastic models such as mixture models, graphical models, Markov random fields and hidden Markov models have key role in probabilistic data analysis. In this paper, we have learned Gaussian mixture model to the pixels of an image. The parameters of the
Rahman Farnoosh, Behnam Zarpak
doaj   +2 more sources

Bootstrap confidence intervals of process capability indices Cpy and CNpmk using different methods of estimation for Frechet distribution

Frontiers in Applied Mathematics and Statistics
Process capability analysis is the statistical evaluation of process capability to examine how well it meets or exceeds the customers satisfaction. In present work, we are intended to evaluate two critical metrics for process quality assessment, Cpy and ...
Tahira Kanwal, Kamran Abbas, Mehwish Zaman, Zamir Hussain   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Objective Bayesian Search of Gaussian DAG Models with Non-local Priors [PDF]

Directed Acyclic Graphical (DAG) models are increasingly employed in the study of physical and biological systems, where directed edges between vertices are used to model direct influences between variables.
Davide Altomare, Luca La Rocca, Guido Consonni   +2 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Robust tightly coupled MLS–ALS fusion with 2D and 3D LiDAR using local geometric uncertainty for accurate 3D mapping

Science of Remote Sensing
Accurate, high-resolution 3D maps are essential for applications such as forestry, infrastructure monitoring, and autonomous navigation. Airborne laser scanning (ALS) provides large-scale coverage but suffers from canopy occlusions, whereas mobile laser ...
Eugeniu Vezeteu, Aimad El Issaoui, Heikki Hyyti, Jesse Muhojoki, Eric Hyyppä, Petri Manninen, Teemu Hakala, Antero Kukko, Harri Kaartinen, Ville Kyrki, Juha Hyyppä   +10 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Semantic-centric change detection framework: considering spatiotemporal heterogeneity and spatiotemporal correlation of land cover

International Journal of Digital Earth
The semantic change detection (SCD) task aims to detect ‘from-to’ change types of land cover occurring over time in registered bitemporal remote sensing images.
Shasha Hou, Guo Zhang, Hao Cui, Xue Li, Yujia Chen, Gui Gao, Bingxuan Guo, Deren Li   +7 more
doaj   +1 more source