Results 101 to 110 of about 5,714,792 (303)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Static behaviour of functionally graded sandwich beams using a quasi-3D theory [PDF]
This paper presents static behaviour of functionally graded (FG) sandwich beams by using a quasi-3D theory, which includes both shear deformation and thickness stretching effects. Various symmetric and non-symmetric sandwich beams with FG material in the
Thai, Huu-Tai +4 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A Refined Theory for Laminated Orthotropic Plates
A refined structural theory is presented which accurately models the static and dynamic behavior of laminated orthotropic plates. The refined theory extends classical theory to include transverse shear, transverse normal, and quadratic displacement terms
R. B. Nelson, D. R. Lorch
core +1 more source
Flexure of thick orthotropic plates by exponential shear deformation theory
In the present paper, a variationally consistent exponential shear deformation theory taking into account transverse shear deformation effect is presented for the flexural analysis of thick orthotropic plates.
A. S. Sayyad
doaj +1 more source
Reflection states in Ding-Iohara-Miki algebra and brane-web for D-type quiver
Reflection states are introduced in the vertical and horizontal modules of the Ding-Iohara-Miki (DIM) algebra (quantum toroidal gl1 $$ \mathfrak{g}{\mathfrak{l}}_1 $$).
J.-E. Bourgine +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Refined compression field theory for plastered straw bale walls
Results of tests of plastered straw bale wall assemblies under in-plane shear and axial load are used together with proposed refinements to compression field theories for reinforced concrete members to predict ultimate shear strengths of plastered ...
PALERMO, MICHELE +3 more
core +1 more source
Flexure Analysis of Functionally Graded Plates Using {2,2}-Refined Zigzag Theory
This study investigates the flexure analysis of functionally graded (FG) plates using {2,2}-refined zigzag plate theory which considers transverse normal deformation along the thickness of plates.
Mehmet Dorduncu
doaj

