Results 91 to 100 of about 5,714,792 (303)

A Novel Neutrosophic Multi-Layered Complex Refined Hyperstructure: Theoretical Advancement with Illustrative Examples from Employee Mental Health Education Effectiveness in Enterprises [PDF]

Neutrosophic Sets and Systems
This paper introduces a new theoretical structure in neutrosophic set theory called the Neutrosophic Multi-Layered Complex Refined Hyperstructure (NMCRH).
Min Zhang, Yaozu Wang, Rui Huang, Qiao Wu, Bingqing Li   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Refined BPS numbers on compact Calabi-Yau threefolds from Wilson loops

Journal of High Energy Physics
We relate the counting of refined BPS numbers on compact elliptically fibred Calabi-Yau threefolds X to Wilson loop expectations values in the gauge theories that emerge in various rigid local limits of the 5d supergravity theory defined by M-theory ...
Min-xin Huang, Sheldon Katz, Albrecht Klemm, Xin Wang   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Analysis of the third-order structuring of Shalom Schwartz’s theory of basic human values

Heliyon, 2019
Shalom Schwartz's Theory of Basic Human Values is one of the most commonly used and tested transcultural theories in the field of behavioural research. This theory has been refined since the 1980s to reach its most recent version, from 2012.
August Corrons Giménez, Lluís Garay Tamajón   +1 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Refining Theories of Change

Journal of MultiDisciplinary Evaluation, 2018
Background: Despite the disparities in how they are defined and what elements are included, most Theories of Change remain consistent in one way – their visual format. Typically, Theories of Change are presented as a one-page visual in a flowchart style with lines and boxes of uniform size.
Lovely Dhillon, Sara Vaca
openaire   +2 more sources

Neutrosophication as a General Framework for Regret Theory, Grey System Theory, and Three-Way Decision Models

Neutrosophic Sets and Systems
Neutrosophy represents a comprehensive philosophical and mathematical framework for the study of neutrality, indeterminacy, and the interaction between opposites.
Florentin Smarandache
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Rousseau on refined Epicureanism and the problem of modern liberty

, 2018
First published: 12 August 2018This article argues that in order to understand the form of modern political freedom envisioned by Rousseau, we have to understand his theory of taste as refined Epicureanism. Rousseau saw the division of labour and corrupt
HOLLEY, Jared
core   +1 more source