Results 81 to 90 of about 112,147 (264)

Reflection states in Ding-Iohara-Miki algebra and brane-web for D-type quiver

open access: yesJournal of High Energy Physics, 2017
Reflection states are introduced in the vertical and horizontal modules of the Ding-Iohara-Miki (DIM) algebra (quantum toroidal gl1 $$ \mathfrak{g}{\mathfrak{l}}_1 $$).
J.-E. Bourgine   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Flexure of thick orthotropic plates by exponential shear deformation theory

open access: yesLatin American Journal of Solids and Structures
In the present paper, a variationally consistent exponential shear deformation theory taking into account transverse shear deformation effect is presented for the flexural analysis of thick orthotropic plates.
A. S. Sayyad
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Flexure Analysis of Functionally Graded Plates Using {2,2}-Refined Zigzag Theory

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2019
This study investigates the flexure analysis of functionally graded (FG) plates using {2,2}-refined zigzag plate theory which considers transverse normal deformation along the thickness of plates.
Mehmet Dorduncu
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Resurgent Wilson loops in refined topological string

open access: yesJournal of High Energy Physics
We study the resurgent structures of Wilson loops in refined topological string theory. We argue that the Borel singularities should be integral periods, and that the associated Stokes constants are refined Donaldson-Thomas invariants, just like the free
Jie Gu, Gengbei Guo
doaj   +1 more source

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