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Gabapentin for Refractory Chronic Cough [PDF]

Lancet, The, 2013
www.thelancet.com Vol 381 February 23, 2013 623 Submissions should be made via our electronic submission system at http://ees.elsevier.com/ thelancet/ pneumonia. Indeed, in our outpatient clinics in Yaita (Tochigi Prefecture) and Kashiwa (Chiba Prefecture), about 20% of patients complaining of persistent cough between June and October, 2012, were ...
Ken-Ichiro Inoue, Hirohisa Takano
exaly   +13 more sources

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Pharmacotherapeutic Options for Chronic Refractory Cough

Expert Opinion on Pharmacotherapy, 2020
Chronic refractory cough (CRC) is more than a persistent cough, but can cause serious impairment to quality of life. Through remarkable advances in our understanding of the neurobiology of cough, there is realization that CRC can be controlled by novel drugs that target cough reflex pathways.The authors present an overview of the clinical trials of ...
Kian Fan Chung, Woo-Jung Song
exaly   +3 more sources

Productive Cough, a Forgotten Phenotype of Refractory Chronic Cough

Monitoring airway disease, 2021
Refractory chronic cough (RCC) patients typically complain of a dry cough. Sputum production in these patients has rarely been described in the literature. However, sputum production in RCC may be common, troublesome and particularly challenging to manage.We aimed to characterise patients referred to our regional specialist cough clinic who have ...
Jenny King, James Wingfield Digby, Sarah Hennessey, Paul Marsden, Jaclyn Smith   +4 more
openaire   +3 more sources

Gabapentin: A Suppressant for Refractory Chronic Cough

Lancet, The, 2012
Kian Fan Chung
exaly   +3 more sources

Bronchoscopy for refractory/unexplained cough with mucus

Respiratory Medicine, 2023
Refractory/unexplained cough (RUCC) is typically associated with throat symptoms and a dry cough. Some patients attending specialist cough clinics however, report sputum production (>1 tablespoon daily) and atypical sensations (urge-to-cough in chest).
James Wingfield Digby, Jenny King, Bashar Al-Sheklly, Paul Marsden, Steve Fowler, Jaclyn Smith   +5 more
openaire   +3 more sources

Management of chronic refractory cough

BMJ, 2015
Chronic refractory cough (CRC) is defined as a cough that persists despite guideline based treatment. It is seen in 20-46% of patients presenting to specialist cough clinics and it has a substantial impact on quality of life and healthcare utilization. Several terms have been used to describe this condition, including the recently introduced term cough
Gibson, Peter G., Vertigan, Anne E.
openaire   +2 more sources

Fiberoptic Bronchoscopy for Refractory Cough

Chest, 1991
Fiberoptic bronchoscopy (FB) has a low yield in the diagnosis of chronic cough (greater than 3 weeks) in unselected patients. We assessed the yield of FB for cough during a four-year period in patients with nonlocalizing chest roentgenograms who were refractory to diagnostic efforts and empiric bronchodilator or antitussive therapy.
R P, Sen, T E, Walsh
openaire   +2 more sources

Lingual tonsillectomy for refractory paroxysmal cough

International Journal of Pediatric Otorhinolaryngology, 2000
Historically, the lingual tonsils are the most neglected members of Waldeyer's ring. They are often overlooked even in a thorough head and neck exam because of their anatomic location and the ambiguous constellation of symptoms which they produce when they are diseased or enlarged.
M, Lewis, J E, McClay, P, Schochet
openaire   +2 more sources

Treatment of Chronic, Refractory Cough with Baclofen

Respiration, 1998
Chronic, nonproductive cough may result from enhanced sensitivity of the cough reflex. Often, this debilitating symptom is refractory to standard antitussive therapy. Baclofen, an agonist of γ-aminobutyric acid (GABA), has been shown, in animals, to have antitussive activity via a central mechanism.
P V, Dicpinigaitis, K, Rauf
openaire   +2 more sources