Results 31 to 40 of about 22,352 (301)

Fully Coherent X-ray Pulses from a Regenerative Amplifier Free Electron Laser

open access: yes, 2006
We propose and analyze a novel regenerative amplifier free electron laser (FEL) to produce fully coherent x-ray pulses. The method makes use of narrow-bandwidth Bragg crystals to form an x-ray feedback loop around a relatively short undulator.
B. Adams   +3 more
core   +2 more sources

High-repetition-rate and high-power efficient picosecond thin-disk regenerative amplifier

open access: yesHigh Power Laser Science and Engineering
We present an effective approach to realize a highly efficient, high-power and chirped pulse amplification-free ultrafast ytterbium-doped yttrium aluminum garnet thin-disk regenerative amplifier pumped by a zero-phonon line 969 nm laser diode.
Sizhi Xu   +11 more
doaj   +1 more source

Highly sensitive multichannel spectrometer for subpicosecond spectroscopy in the midinfrared [PDF]

open access: yes, 1994
A spectrometer system is presented for time-resolved probing in the midinfrared between 5 and 11 /tLmw ith a temporal resolution of better than 400 fs.
Hamm, P.   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A versatile high-average-power ultrafast infrared driver tailored for high-harmonic generation and vibrational spectroscopy

open access: yesScientific Reports, 2023
We report on an ultrafast infrared optical parametric chirped-pulse amplifier (OPCPA), pumped by a 200-W thin-disk Yb-based regenerative amplifier at a repetition rate of 100 kHz.
Nicolas Thiré   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ultrafast high power Yb:KLuW regenerative amplifier

open access: yesOptics Express, 2009
We report on an high power ultra-short pulse regenerative Yb:KLuW amplifier based on the thin disk concept. A maximum pulse energy of 571 microJ was extracted at a repetition rate of 20 kHz. Compression of the output pulses resulted in a pulse duration of 197 fs assuming a deconvolution factor of 2.16.
H, Sayinc   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A rail‐to‐rail regenerative comparator with inverse inverter pre‐amplifier for low supply voltage applications

open access: yesElectronics Letters, 2023
In this letter, a new rail‐to‐rail two‐stage regenerative comparator for low supply voltage applications is presented. A rail‐to‐rail operation is achieved by utilizing an inverse inverter pre‐amplifier.
Hadi Pahlavanzadeh   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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