Results 181 to 190 of about 45,362 (276)

Origin of Substituent-Modulated Regioselectivity in Phosphine-Catalyzed [3 + 2] Cyclization of Allenoates and Enones: A Kinetic Shift toward Curtin-Hammett Control. [PDF]

J Org Chem
Huang GT, Yu JK.
europepmc   +1 more source

TailoringGold Corroles via Regioselective Nitration:Near Infrared Emission, Singlet Oxygen Sensitization, and PhotocatalyticOxidation of Sulfides

Subhajit Kar (10132261), Tanmoy Pain (11327236), Rwiddhi Chakraborty (19959634), Pravansu Panda (21525498), Narayan Ch. Jana (10342687), Sanjib Kar (1716496)   +5 more
openalex   +1 more source

Myths and Truths About Electrophilic Aromatic Substitution: The Particular Case of Fluorobenzene

Journal of Physical Organic Chemistry, Volume 39, Issue 2, February 2026.
Nitration σ‐complex formation is exothermic, and halogens—particularly fluorine—enhance para reactivity, challenging traditional descriptions of halogens as purely deactivating in EAS. ABSTRACT Electrophilic aromatic substitution (EAS) is a fundamental reaction introduced early in organic chemistry courses, highlighting the influence of substituents on
Francisco A. Martins, Matheus P. Freitas   +1 more
wiley   +1 more source

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom‐Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Strained spirocyclic spiro[2.3]hexane and its heteroatom‐containing derivatives, including previously underrepresented 5‐oxa‐1‐azaspiro[2.3]hexanes and 1,5‐diazaspiro[2.3]hexanes, were synthesized via a modular approach of insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into alkenes, carbonyls and imines.
Philipp Natho, Annarita Vicenti, Fabrizio Mastrolorito, Francesca De Franco, Lee Walsh‐Benn, Marco Colella, Ernesto Mesto, Emanuela Schingaro, Orazio Nicolotti, Antimo Gioiello, Renzo Luisi   +10 more
wiley   +2 more sources

Mo-Catalyzed Asymmetric Allylic Alkylation Enabling the Construction of Highly Enantioenriched 1,4-Dicarbonyl Scaffolds. [PDF]

J Am Chem Soc
Cerione CS, Moghadam FA, Stoltz BM.
europepmc   +1 more source

D‐Optimal Design for Enzymatic Ring‐Opening Polymerization of ε‐Caprolactone: Toward Sustainable Polyester Synthesis Using Biobased Solvents

Journal of Polymer Science, Volume 64, Issue 3, Page 817-824, 1 February 2026.
A D‐optimal design of experiments maps the influence of key reaction parameters on enzymatic ε‐caprolactone polymerization. Thus linking multivariate conditions to conversion, molar mass characteristics, and by‐product formation, whilst demonstrating that biobased solvents offer viable, sustainable media for polyester synthesis.
Emily G. Dixon, Emily Chau, Luisa Ciano, Anca Pordea, Karen Alvey, Vincenzo Taresco   +5 more
wiley   +1 more source

A Radical Cascade with Double Intramolecular Hydrogen Atom Transfer for the Generation of Bisfunctionalized Cyclopentanes from Linear Alkynes

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
A radical cascade process involving the activation of two aliphatic C–H bonds in a series of five elementary steps converts readily available terminal alkynes into functionalized cyclopentylmethyl arylsulfones. The methodology delivers flexible synthetic intermediates and was applied to the preparation of diquinanes and triquinanes possessing a rare ...
Lise Benoist, Éléonore Barbier, Mariam Sangare, Philippe Renaud, Fabrice Dénès   +4 more
wiley   +2 more sources

Coordination-Accelerated Catalysis in the Heck Reaction Using N-H <i>N</i>-Heterocyclic Carbene Pd Complexes. [PDF]

J Org Chem
Harper AP, Larson AJS, Brown LM, Owens RN, Noble KL, Villarreal-Quiroga GH, Michaelis DJ.   +6 more
europepmc   +1 more source

Estrone‐α‐2‐Deoxy‐Glucoside as a Targeted Therapy for Triple‐Negative Breast Cancer: Aromatase Inhibition and Cytotoxicity

Chemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Estrone‐α‐2DG, synthesized via a one‐pot multi‐enzyme system, selectively inhibits aromatase (IC50 = 0.101μM) and triple negative breast cancer cells (IC50 = 20.46 μM), offering a dual function therapeutic scaffold. ABSTRACT Aromatase inhibitors (AIs) are vital in the treatment of estrogen‐dependent breast cancer, especially in postmenopausal women. In
Tzu‐Yu Huang, Meng‐Ru Wang, Feng‐Pai Chou, Sheng‐Cih Huang, Po‐Yun Hsiao, Tung‐Kung Wu   +5 more
wiley   +1 more source

Synthesis of a series of vicinal diamines with potential biological activity

Open Chemistry, 2004
Kurteva Vanya, Lyapova Maria
doaj   +1 more source