Results 81 to 90 of about 722,064 (339)

Model consent clauses for rare disease research [PDF]

open access: yes, 2019
Background: Rare Disease research has seen tremendous advancements over the last decades, with the development of new technologies, various global collaborative efforts and improved data sharing.
Goldblatt, Jack   +15 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Credit reporting and financing constraints [PDF]

open access: yes
The authors combine firm-level data from the World Bank Business Environment Survey (WBES) with data on private and public credit registries to investigate whether the presence of a credit registry in a country is associated with lower financing ...
Inessa Love, Nataliya Mylenko
core  

Patient-reported outcome measures in arthroplasty registries

open access: yesActa Orthopaedica, 2016
The International Society of Arthroplasty Registries (ISAR) Steering Committee established the Patient-Reported Outcome Measures (PROMs) Working Group to convene, evaluate, and advise on best practices in the selection, administration, and interpretation
O. Rolfson   +11 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Electronic titling: Potential and risks [PDF]

open access: yes
Initiatives in electronic conveyancing and registration show the potential of new technologies to transform such systems, reducing costs and enhancing legal security.
Benito Arruñada
core  

Learning from registries in pulmonary arterial hypertension: pitfalls and recommendations

open access: yesEuropean Respiratory Review, 2019
Pulmonary arterial hypertension is a rare and incurable chronic disease characterised by a progressive increase in pulmonary vascular resistance and right heart failure.
K. Swinnen   +4 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

A mathematical model for bone marrow donors' registries and cord blood banks [PDF]

open access: yes
This paper constructs an economic analysis of some organ donation organizations. The two main examples are voluntary marrow donor registries and cord blood banks.
Florens, Jean-Pierre   +1 more
core  

Revisiting Alaska's Sex Offender Registration and Public Notification Statute [PDF]

open access: yes, 2008
Originally published in the Alaska Justice Forum 25(1–2): 2–5 (Spring/Summer 2008)This article examines the background and judicial interpretation of Alaska's sex offender registration and public notification statute, the new federal requirements for ...
Periman, Deborah
core   +1 more source

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