Results 21 to 30 of about 1,600,466 (167)

Galectin genes: Regulation of expression

open access: yesGlycoconjugate Journal, 2002
In this review we have summarized the more recent studies on the expression of mammalian galectins. One interesting observation that can be made is that in most of microarrays and/or differential display analysis performed in recent years one or more galectins have been picked up.
CHIARIOTTI, LORENZO   +3 more
openaire   +4 more sources

The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation

open access: yesOpen Biology, 2021
Treslin/Ticrr is required for the initiation of DNA replication and binds to MTBP (Mdm2 Binding Protein). Here, we show that in Xenopus egg extract, MTBP forms an elongated tetramer with Treslin containing two molecules of each protein.
Ilaria Volpi   +3 more
doaj   +1 more source

The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element

open access: yesGenome Biology, 2017
Background It is now obvious that the majority of cellular transcripts do not code for proteins, and a significant subset of them are long non-coding RNAs (lncRNAs).
Oskar Marín-Béjar   +12 more
doaj   +1 more source

A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

open access: yesNature Communications, 2020
SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional ...
Elena Grossi   +8 more
doaj   +1 more source

Dynamics of Whole-Genome Contacts of Nucleoli in Drosophila Cells Suggests a Role for rDNA Genes in Global Epigenetic Regulation

open access: yesCells, 2020
Chromosomes are organized into 3D structures that are important for the regulation of gene expression and differentiation. Important role in formation of inter-chromosome contacts play rDNA clusters that make up nucleoli. In the course of differentiation,
Nickolai A. Tchurikov   +7 more
doaj   +1 more source

Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development

open access: yesScientific Reports, 2017
Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C.
Sarah-Lena Offenburger   +4 more
doaj   +1 more source

Gene expression regulation and cancer

open access: yesClinical and Translational Oncology, 2006
Gene expression is mostly controlled at the level of the transcription initiation. The transcription control regions of protein-encoding genes include: the core promoter, where RNA polymerase II binds, the proximal and distal promoter, responsible for gene expression regulation, and the enhancers and silencers.
Delgado, M. Dolores, León, Javier
openaire   +4 more sources

Efficient and Rapid Analysis of Polysomes and Ribosomal Subunits in Cells and Tissues Using Ribo Mega-SEC

open access: yesBio-Protocol, 2021
Polysome profile analysis is a popular method for separating polysomes and ribosomal subunits and is typically achieved using a sucrose density gradient (SDG).
Harunori Yoshikawa   +4 more
doaj   +1 more source

Regulated gene expression in methanogens [PDF]

open access: yesFEMS Microbiology Reviews, 1994
Methanogens form a very large and diverse group of microorganisms within the domain of the Archaea. Energy for their growth is obtained by the reduction of a variety of substrates into methane. Several genes, coding for enzymes involved in methanogenesis or in the central metabolism have been cloned and studied.
openaire   +3 more sources

ARID1A promotes genomic stability through protecting telomere cohesion

open access: yesNature Communications, 2019
Cells with ARID1A mutations exhibit mitotic defects, yet show surprisingly low levels of copy number defects. Here, Zhao et al. resolve this issue by showing that ARID1A loss causes defects in telomere cohesion, which selects against gross alterations in
Bo Zhao   +16 more
doaj   +1 more source

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