Results 21 to 30 of about 5,141,166 (402)
Azole Resistance-Associated Regulatory Motifs within the Promoter of cyp51A in Aspergillus fumigatus
Microbiology Spectrum, 2022 Aspergillus fumigatus is one of the deadliest fungal species, causing hundreds of thousands of deaths each year. Because azoles provide the preferred first-line option for treatment of aspergillosis, the increase in rates of resistance and the poor ...
Alexander Kühbacher +7 more
doaj +1 more source
Mechanisms of robustness in gene regulatory networks involved in neural development
Frontiers in Molecular Neuroscience, 2023 The functions of living organisms are affected by different kinds of perturbation, both internal and external, which in many cases have functional effects and phenotypic impact.
Camila D. Arcuschin +4 more
doaj +1 more source
Conservation of mRNA and Protein Expression during Development of C. elegans
Cell Reports, 2014 Spatiotemporal control of gene expression is crucial for development and subject to evolutionary changes. Although proteins are the final product of most genes, the developmental proteome of an animal has not yet been comprehensively defined, and the ...
Dominic Grün +5 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Bacteria belonging to Streptomyces have the ability to produce a wide range of secondary metabolites through a shift from primary to secondary metabolism regulated by complex networks activated after vegetative growth terminates.
Soonkyu Hwang +22 more
doaj +1 more source
Latent regulatory potential of human-specific repetitive elements [PDF]
, 2013 At least half of the human genome is derived from repetitive elements, which are often lineage specific and silenced by a variety of genetic and epigenetic mechanisms. Using a transchromosomic mouse strain that transmits an almost complete single copy of
Barbosa-Morais, Nuno L. +15 more
core +1 more source
Cell fixation and preservation for droplet-based single-cell transcriptomics
BMC Biology, 2017 Background Recent developments in droplet-based microfluidics allow the transcriptional profiling of thousands of individual cells in a quantitative, highly parallel and cost-effective way.
Jonathan Alles +12 more
doaj +1 more source
Tracing tumorigenesis in a solid tumor model at single-cell resolution
Nature Communications, 2020 Understanding tumour development at a granular level is a challenge in solid tumours. Here, the authors provide a cell atlas across tumour development in a genetic model of salivary gland squamous cell carcinoma using single-cell transcriptome and ...
Samantha D. Praktiknjo +9 more
doaj +1 more source
Nucleic Acids Res., 2002 PlantCARE is a database of plant cis-acting regulatory elements, enhancers and repressors. Regulatory elements are represented by positional matrices, consensus sequences and individual sites on particular promoter sequences.
M. Lescot +7 more
semanticscholar +1 more source
Regulatory elements in molecular networks
WIREs Systems Biology and Medicine, 2017 Regulatory elements determine the connectivity of molecular networks and mediate a variety of regulatory processes ranging from DNA looping to transcriptional, posttranscriptional, and posttranslational regulation. This review highlights our current understanding of the different types of regulatory elements found in molecular networks with a focus on ...
A. Doane, O. Elemento
semanticscholar +5 more sources
Regulatory Elements of TRPA1 Function [PDF]
Biophysical Journal, 2009 Transient Receptor Potential Ankyrin 1 channel, TRPA1, is a member of the TRP family and has been shown to be expressed in dorsal root ganglions, trigeminal ganglion neurons and hair cells. TRPA1 is proposed to play an important role in pain perception and temperature sensing, and might be involved as transduction channel in mechanosensation essential ...
Rainer Schindl +5 more
openaire +2 more sources