Results 61 to 70 of about 5,141,166 (402)
The C-terminus of p63 contains multiple regulatory elements with different functions [PDF]
, 2010 The transcription factor p63 is expressed as at least six different isoforms, of which two have been assigned critical biological roles within ectodermal development and skin stem cell biology on the one hand and supervision of the genetic stability of ...
Candi, Eleonora +8 more
core +2 more sources
Frontiers in Oncology, 2020 ETS1 has shown dichotomous roles as an oncogene and a tumor suppressor gene in diverse cancers, but its functionality in breast cancer tumorigenesis still remains unclear.
Gi-Cheon Kim +13 more
doaj +1 more source
Nature Communications, 2019 The majority of common variants associated with common diseases, as well as an unknown proportion of causal mutations for rare diseases, fall in noncoding regions of the genome.
Martin Kircher +8 more
semanticscholar +1 more source
Hunting for Cis-Regulatory Elements in Proteins [PDF]
Cell Systems, 2016 A new bioinformatics tool predicts natively disordered protein control elements that function in cis, opening the door to more systematic studies of this biomedically important class of protein modules.
Manjeet Kumar, Toby J. Gibson
openaire +3 more sources
Regulatory elements in the viral genome
Virology, 2013 The small DNA genomes of papillomaviruses contain a surprisingly large number of regulatory or cis-responsive elements, which regulate replication and transcription of the virus, and control details like specificity for certain epithelial cells, specificity for layers in squamous epithelia, feedback mechanisms and coupling between host cell physiology ...
openaire +3 more sources
Modular arrangement of regulatory RNA elements [PDF]
RNA Biology, 2017 Due to their simple architecture and control mechanism, regulatory RNA modules are attractive building blocks in synthetic biology. This is especially true for riboswitches, which are natural ligand-binding regulators of gene expression. The discovery of various tandem riboswitches inspired the design of combined RNA modules with activities not yet ...
Franz Narberhaus, Johanna Roßmanith
openaire +3 more sources
Identification of candidate regulatory sequences in mammalian 3' UTRs by statistical analysis of oligonucleotide distributions [PDF]
, 2007 3' untranslated regions (3' UTRs) contain binding sites for many regulatory elements, and in particular for microRNAs (miRNAs). The importance of miRNA-mediated post-transcriptional regulation has become increasingly clear in the last few years.
Caselle, Michele +3 more
core +4 more sources
ENCODE: A Sourcebook of Epigenomes and Chromatin Language [PDF]
Genomics & Informatics, 2013 Until recently, since the Human Genome Project, the general view has been that the majority of the human genome is composed of junk DNA and has little or no selective advantage to the organism.
Maryam Yavartanoo, Jung Kyoon Choi
doaj +1 more source
Network topology drives population temporal variability in experimental habitat networks
Population Ecology, EarlyView.Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu +3 more
wiley +1 more source
Notulae Scientia Biologicae, 2018 Salicylic acid (SA) and jasmonic acid (JA) phytohormones have been known for their roles in plant defense behaviour against biotic and abiotic stresses. They regulate defense pathways by antagonistic interaction.
Amir G. SHAHRIARI +2 more
doaj +1 more source