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Immunotherapy of cancer without induction of autoimmunity - CD6 as a therapeutic target. [PDF]
Front ImmunolFox DA, Gurrea-Rubio M.
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Spatial Immune Remodeling Across the Gallbladder Carcinogenesis Spectrum: A Multicenter Digital Pathology Study. [PDF]
World J OncolKveliashvili T +3 more
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Reduced regulatory T lymphocytes in migraine patients
Neurological Research, 2021Objectives: Migraine is a primary headache disorder with unknown pathophysiology. Recently, many studies have suggested the role of immune dysfunction in the pathophysiology of this disorder. In this study, we investigated the percentage of regulatory T cells (Treg cells) in different migraine categories.Methods: Peripheral blood samples of 40 newly ...
Fardin Faraji +4 more
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The Role of Recombinant Glycodelin in the Differentiation of Regulatory T-Lymphocytes
Doklady Biological Sciences, 2022The effect of recombinant glycodelin (GdA) on the number of T-regulatory lymphocytes (Treg) in a culture of activated CD4+ lymphocytes was investigated, while simultaneously assessing the proliferative status of the cells. Recombinant GdA from E. coli and from HEK293 cells were used in the study at concentrations of 0.2; 2 and 10 µg/mL.
K Yu, Shardina +5 more
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The regulatory network that controls the differentiation of T lymphocytes
BioSystems, 2013There is a vast amount of molecular information regarding the differentiation of T lymphocytes, in particular regarding in vitro experimental treatments that modify their differentiation process. This publicly available information was used to infer the regulatory network that controls the differentiation of T lymphocytes into CD4(+) and CD8(+) cells ...
Luis Mendoza
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Regulatory Role of T Lymphocytes in Atopic Dermatitis
2008Eczema does not occur in the absence of T cells. Here we provide an overview on the regulatory impact which T cells have on the establishment and maintenance of atopic dermatitis. Particularly, we outline the role of different T-helper cell subsets (i.e.
T, Werfel, M, Wittmann
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Murine CD8+ regulatory T lymphocytes: The new era
Human Immunology, 2008Regulatory T lymphocytes unequivocally play a major role in the maintenance of immunologic homeostasis. The first descriptions of regulatory T lymphocytes concerned CD8(+) cells, but this field was brought into discredit when some of its central tenets turned out to be erroneous. CD4(+) regulatory T cells took over and, with the help of newly developed
Céline, Pomié +2 more
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The role of regulatory t lymphocytes in asthma pathogenesis
Current Allergy and Asthma Reports, 2005Several subtypes of regulatory or suppressive T cells have been described that can prevent activation of effector T cells in vitro and in vivo in animal models. Recent evidence suggests a deficit in suppressive activity of both CD4(+)CD25(+) regulatory T cells, and interleukin (IL)-10 producing regulatory T cells may play a role in development of ...
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Development of Thymic Regulatory T Lymphocytes
2019A healthy immune system should maintain a balance between the ability to respond to infectious agents and tumor cells at the same time that sustains self-tolerance. For this purpose, the immune system must be capable of restraining foreign antigens, stopping the immune response after the resolution of a problem and blocking autoreactivity of immune ...
Larissa Vasconcelos-Fontes +4 more
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