REGULATORY INFLUENCE OF THYMOPENTIN ON SPLENIC T CELL SETS OF THYMECTOMIZED AND AGED MICE1,2
, 1985 Elizabeth W. Newcomb +5 more
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Inactivation of T cell receptor peptide-specific CD4 regulatory T cells induces chronic experimental autoimmune encephalomyelitis (EAE). [PDF]
, 1996 Vipin Kumar +2 more
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Transforming Growth Factor β (TGF-β)-dependent Inhibition of T Helper Cell 2 (Th2)-induced Autoimmunity by Self–Major Histocompatibility Complex (MHC) Class II–specific, Regulatory CD4+ T Cell Lines [PDF]
, 1997 Frank Bridoux +7 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Regulatory T cell therapy for xenotransplantation, what perspectives? [PDF]
Front ImmunolPorret R +10 more
europepmc +1 more source
Peripheral Autoantigen Induces Regulatory T Cells that Prevent Autoimmunity [PDF]
, 1999 Benedict Seddon, Don Mason
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Regulatory T cell therapy for Sjögren's disease: From pathogenesis to targeted treatment. [PDF]
J Transl AutoimmunLim ZFS +6 more
europepmc +1 more source
Effect of SLE anti-T cell antibodies on regulatory T cells
, 1980 Tsuyoshi Sakane +3 more
openalex +2 more sources