Results 231 to 240 of about 2,996,073 (354)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

United multi-omics and machine learning refine regulatory T cell-defined hepatocellular carcinoma subtypes. [PDF]

iScience
Zhang W, Liu C, Jin A, Shen M.
europepmc   +1 more source

Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

Science Signaling, 2015
Dorota Klysz, X. Tai, Philippe A. Robert, Marco Craveiro, Gaspard Cretenet, Leal Oburoglu, Cédric Mongellaz, S. Floess, V. Fritz, M. Matias, C. Yong, Natalie H. Surh, J. Marie, J. Huehn, V. Zimmermann, S. Kinet, V. Dardalhon, N. Taylor   +17 more
semanticscholar   +1 more source

Integrated transcriptomic, metabolomic and lipidomic analysis revealed unique metabolic profile of regulatory T cells upon activation 3421 [PDF]

Yohei Sato, Misa Yura, Y Hanawa, Akihito Tsubota   +3 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The molecular mechanisms for regulatory T cell immunosuppression

Frontiers in Immunology, 2012
Kendall A Smith
doaj   +1 more source

Development of a humanized mouse model of graft-versus-host disease to assess human regulatory T cell function. [PDF]

Front Immunol
Beguin C, Kwan O, Ehx G, Humblet-Baron S, Köse MC, Dubois S, Canti L, Courtois J, Daulne C, Caers J, Beguin Y, Ritacco C, Baron F.   +12 more
europepmc   +1 more source

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.

Immunity, 2009
Greg M. Delgoffe, T. Kole, Yan Zheng, Paul E. Zarek, Krystal L. Matthews, B. Xiao, P. Worley, S. Kozma, J. Powell   +8 more
semanticscholar   +1 more source

Table S8 from CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer

Stéphane Fattori, Aude Le Roy, Jemila Houacine, Lucie Robert, Riad Abès, Laurent Gorvel, Samuel Granjeaud, Marie-Sarah Rouviére, Amira Ben Amara, Nicolas Boucherit, Carole Tarpin, Jihane Pakradouni, Emmanuelle Charafe‐Jauffret, Gilles Houvenaeghel, Éric Lambaudie, François Bertucci, Philippe Rochigneux, Anthony Gonçalvès, Arnaud Foussat, Anne-Sophie Chrétien, Daniel Olive   +20 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source