Results 221 to 230 of about 1,033,187 (394)

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

Advanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang, Matthew C. Hill, Mingxing He, Junhao Chen, Zirui Wang, Patrick T. Ellinor, Min Li   +6 more
wiley   +1 more source

Generation and characterization of a continuous line of CD8+ suppressively regulatory T lymphocytes which down-regulates experimental autoimmune orchitis (EAO) in mice

, 1994
Akiko Mukasa, Chiharu Hiramine, Kenji Hojo   +2 more
openalex   +2 more sources

Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma [PDF]

, 2003
Neil A. Marshall, Linsey Christie, Laura Munro, Dominic Culligan, Peter Johnston, Robert N. Barker, Mark A. Vickers   +6 more
openalex   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Spironolactone Decreases DOCA–Salt–Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes

HYPERTENSION, 2014
C. Amador, Víctor Barrientos, J. Peña, A. Herrada, Magdalena González, S. Valdes, Loreto Carrasco, R. Alzamora, F. Figueroa, A. Kalergis, L. Michea   +10 more
semanticscholar   +1 more source

Electrical Microneedles for Wound Treatment

Advanced Science, EarlyView.
A review on state‐of‐art research concerning electrical microneedles applied for wound treatment is presented. After a comprehensive analysis of mechanisms of electrical stimulation on wound healing, the derived three types of electrical microneedles are clarified and summarized. Further, their applications in wound healing are highlighted.
Yu Wang, Lijun Cai, Lu Fan, Li Wang, Feika Bian, Weijian Sun, Yuanjin Zhao   +6 more
wiley   +1 more source

Biochemical Analysis of the Regulatory T Cell Protein Lymphocyte Activation Gene-3 (LAG-3; CD223) [PDF]

, 2004
Nianyu Li, Creg J. Workman, S Martin, Dario A.A. Vignali   +3 more
openalex   +1 more source

Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Cell Transplantation, 2015
E. Vågesjö, G. Christoffersson, Tomas B. Waldén, P. Carlsson, M. Essand, O. Korsgren, M. Phillipson   +6 more
semanticscholar   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van der Veen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
wiley   +1 more source

The Prognostic Impact of Circulating Regulatory T Lymphocytes on Mortality in Patients with Ischemic Heart Failure with Reduced Ejection Fraction. [PDF]

Mediators Inflamm, 2020
Hammer A, Sulzgruber P, Koller L, Kazem N, Hofer F, Richter B, Blum S, Hülsmann M, Wojta J, Niessner A.   +9 more
europepmc   +1 more source