Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension
A. Huertas+11 more
semanticscholar +1 more source
Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen+9 more
wiley +1 more source
Regulatory T lymphocytes as a treatment method for rheumatoid arthritis - Superiority of allogeneic to autologous cells. [PDF]
Chmiel J+5 more
europepmc +1 more source
CDK4: Regulatory functions related to lymphocytes [PDF]
Patricia W. Finn+2 more
openaire +2 more sources
Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen+16 more
wiley +1 more source
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui+17 more
wiley +1 more source
Peripheral and intestinal T lymphocyte subsets in dogs with chronic inflammatory enteropathy [PDF]
Background: Dysregulated T lymphocyte response is thought to play a key role in chronic intestinal inflammation (CIE). Objectives: To evaluate the presence of changes in peripheral and intestinal T lymphocyte subsets and to describe potential immune ...
Agulla, Beatriz+7 more
core
Initial depletion of regulatory T cells: the missing solution to preserve the immune functions of T lymphocytes designed for cell therapy [PDF]
Mariana Mesel‐Lemoine+7 more
openalex +1 more source
Loss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases. [PDF]
Wójcik M+24 more
europepmc +1 more source