Results 61 to 70 of about 1,033,187 (394)

CD8+ T Lymphocytes: Crucial Players in Sjögren’s Syndrome

Frontiers in Immunology, 2021
Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease associated with damage to multiple organs and glands. The most common clinical manifestations are dry eyes, dry mouth, and enlarged salivary glands.
Huimin Zhou, Huimin Zhou, Jun Yang, Jie Tian, Shengjun Wang, Shengjun Wang   +5 more
doaj   +1 more source

Regulatory T Lymphocytes (Treg): Modulation and Clinical Application [PDF]

, 2017
Treg cells CD4+CD25+FOXP3+ have a specific function in the tolerance of autoantigens and regulation of the immune response. Modulation of differentiation pathways and the use of Treg cells in cell therapy have been reported in autoimmune diseases ...
Bydlowski, Sérgio Paulo, da Cunha, Joel, Levy, Débora, Maselli, Luciana Morganti Ferreira, Reichert, Cadiele Oliana, Spada, Celso   +5 more
core   +2 more sources

Expression of Interleukin-10 in Intestinal Lymphocytes Detected by an Interleukin-10 Reporter Knockin tiger Mouse [PDF]

, 2006
SummaryTo identify interleukin-10 (IL-10)-producing cells in vivo, we generated a knockin mouse where an internal ribosome entry site (IRES) green fluorescence protein (GFP) element was inserted immediately before the polyadenylation site of the IL-10 ...
Flavell, Richard A., Galán, Jorge E., Harhaj, Ed, Kamanaka, Masahito, Kim, Sean T., Lara-Tejero, Maria, Sutterwala, Fayyaz S., Wan, Yisong Y.   +7 more
core   +1 more source

Dynamic assessment of T-lymphocytes and humoral immunity in patients with acute coronary syndrome, with and without COVID-19, depending on the content of CD3⁺CD8⁺T-lymphocytes

Медицинский вестник Юга России
Objective: to evaluate the dynamics of the T- and B-cell immunity in patients with acute coronary syndrome (ACS) who have and have not had COVID-19, depending on the number of CD3+CD8+T-lymphocytes.Materials and methods: 65 men with ACS who underwent ...
E. A. Safronova, L. V. Ryabova, A. V. Zurochka, M. A. Dobrynina, E. V. Zadorina   +4 more
doaj   +1 more source

Cyclin kinase inhibitor p21: a mediator of immune tolerance: direct and indirect evidence [PDF]

, 2009
*Background:* Uncontrolled proliferation of T-cells is considered a barrier to the induction of transplantation tolerance by T regulatory cells. Therefore, cyclin kinase inhibitor p21, one of the most potent inhibitors of cell proliferation, may exert an
Ashwani Khanna
core   +1 more source

Phase- and Stage-Related Proportions of T Cells Bearing the Transcription Factor FOXP3 Infiltrate Primary Melanoma [PDF]

, 2008
Although tumor-infiltrating lymphocytes (TILs) of primary cutaneous melanoma (PCM) include cytolytic T cells able to exert anti-PCM immunity, progression of PCM most frequently occurs, raising the hypothesis that the PCM microenvironment may also exert ...
Campanini, Nicoletta, De Panfilis, Giuseppe, Ferrari, Donata, Froio, Elisabetta, Lombardi, Mara, Maestri, Roberta, Mori, Giovanni, Ricci, Roberto, Santini, Marcello, Tognetti, Elena   +9 more
core   +1 more source

Associations of T helper 1, 2, 17 and regulatory T lymphocytes with mortality in severe sepsis

Inflammation Research, 2013
Objective and designT helper 17 (Th17) and regulatory T (Treg) lymphocytes might play important roles in patients with severe sepsis. The association of Th17 or Treg lymphocytes with survival is also unclear.MethodsEighty-seven patients with severe ...
Huang-Pin Wu, K. Chung, Chun-Yao Lin, B. Jiang, D. Chuang, Yu‐Chih Liu   +5 more
semanticscholar   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Foxp3+ T-lymphocytes in the pathogenesis of mycosis fungoides

Vestnik Dermatologii i Venerologii, 2017
The pathogenesis of mycosis fungoides (MF) is not fully understood, nevertheless it is believed that the microenvironment of the tumor cells could influence the development of malignant lymphocytes. T-regulatory cells are a specialized subpopulation of T-
A. S. Zhukov, I. E. Belousova, A. V. Samtsov   +2 more
doaj   +1 more source

Islet Lymphocytes Maintain a Stable Regulatory Phenotype Under Homeostatic Conditions and Metabolic Stress

Frontiers in Immunology, 2022
T cells and B cells have been identified in human and murine islets, but the phenotype and role of islet lymphocytes is unknown. Resident immune populations set the stage for responses to inflammation in the islets during homeostasis and diabetes.
Jennifer C. Whitesell, Jennifer C. Whitesell, Jennifer C. Whitesell, Robin S. Lindsay, Robin S. Lindsay, Jessica G. Olivas-Corral, Jessica G. Olivas-Corral, Seth F. Yannacone, Mary H. Schoenbach, Mary H. Schoenbach, Erin D. Lucas, Rachel S. Friedman, Rachel S. Friedman, Rachel S. Friedman   +13 more
doaj   +1 more source