Results 1 to 10 of about 17,493 (160)

Supporting Witnesses and Victims to Invoke Episodic Retrieval Mode: Own-Generated Verbal- and Sketch-Reinstatement-of-Context Retrieval Cues Improves Recall Versus Interviewer-Generated Mental Reinstatement of Context Cues. [PDF]

Behav Sci (Basel)
Background: Criminal justice relies on information from witnesses. Retrieval from episodic memory is cognitively demanding; thus, many interview protocols advocate techniques to support episodic retrieval mode, which is essential for obtaining detailed ...
Dando CJ, Dando RV, Richardson H, Osorio Rojas A, Taylor DA.   +4 more
europepmc   +2 more sources

Threat Conditioning Prior to Cocaine or Sucrose Exposure Alters Reward-Seeking Behavior in a Sex-Dependent Manner. [PDF]

Psychiatry Int (Basel)
Background/Objectives: Research has shown a high prevalence of co-occurring trauma-related disorders and cocaine use disorder (CUD). However, there remains a need for preclinical studies to determine how traumatic event exposure influences vulnerability ...
Perez-Perez Y, Morales-Silva RJ, Rodriguez-Torres GN, Ruiz-Villalobos R, Rivera-Velez JC, Arlequin-Torres EG, Vera-Torres EM, Godoy-Muñoz LJ, Fazal SI, Rivera-Aviles N, Neira S, Sepulveda-Orengo MT.   +11 more
europepmc   +2 more sources

DUSP5 Downregulation in Nucleus Accumbens Core Correlates with Cocaine-Induced Maladaptive Synaptic Plasticity. [PDF]

Cells
The United States is currently facing a drug overdose epidemic. The nucleus accumbens core (NAcore), a brain region critical for reward and aversion behaviors, undergoes structural and functional synaptic adaptations in response to chronic drug exposure.
Taborda-Bejarano JP, Meyerink M, Crans DC, Ramchandran R, Garcia-Keller C.   +4 more
europepmc   +2 more sources

The effect of intracerebroventricular injection of insulin-like growth factor-1 on morphine-induced conditioned place preference extinction and reinstatement; a behavioral and biochemical experimental study. [PDF]

Behav Brain Funct
Background Morphine addiction is a growing problem with severe consequences. Interestingly, Insulin-like Growth Factor-1 (IGF-1), a hormone with the ability to modulate neural pathways and exert neuroprotective and regenerative properties, could emerge ...
Ghadirzadeh E, Gheibi M, Siahposht-Khachaki A, Vahdati Helan E, Farvardin M, Shadi S, Abdolkarimi A.   +6 more
europepmc   +2 more sources

Glutamate receptor-interacting protein 1 in D1- and D2-dopamine receptor-expressing medium spiny neurons differentially regulates cocaine acquisition, reinstatement, and associated spine plasticity

Frontiers in Cellular Neuroscience, 2022
BackgroundThe nucleus accumbens (NAc) is involved in the expression of cocaine addictive phenotypes, including acquisition, extinction, and reinstatement.
He Chen, Limei Chen, Zhirong Yuan, Jiajie Yuan, Yitong Li, Yuesi Xu, Jieyi Wu, Lu Zhang, Guohua Wang, Juan Li   +9 more
doaj   +1 more source

Intolerance of uncertainty predicts altered threat expectancy ratings during reinstatement

Journal of Experimental Psychopathology, 2022
Intolerance of uncertainty (IU) is a transdiagnostic risk factor for psychiatric disorders, and plays an important role in fear and threat learning under uncertainty.
Daniel V Zuj, Simon Dymond, Stuart B Murray, Shaima Thomas, Jayne Morriss   +4 more
doaj   +1 more source

Multimodal assessment of long-term memory recall and reinstatement in a combined cue and context fear conditioning and extinction paradigm in humans. [PDF]

PLoS ONE, 2013
Learning to predict danger via associative learning processes is critical for adaptive behaviour. After successful extinction, persisting fear memories often emerge as returning fear. Investigation of return of fear phenomena, e.g.
Jan Haaker, Tina B Lonsdorf, Alexandra Thanellou, Raffael Kalisch   +3 more
doaj   +1 more source

Glutamate and reinstatement [PDF]

Current Opinion in Pharmacology, 2009
The importance of glutamate in the reinstatement of cocaine-seeking behavior has been established. New molecular and neurochemical adaptations in the glutamatergic system which drive cocaine relapse have been identified, such as the ability of CB1 receptor stimulation to reduce basal glutamate levels and the involvement of the GluR1 receptor subunit in
Lori A, Knackstedt, Peter W, Kalivas
openaire   +2 more sources

Identification of brain nuclei implicated in cocaine-primed reinstatement of conditioned place preference: a behaviour dissociable from sensitization. [PDF]

PLoS ONE, 2010
Relapse prevention represents the primary therapeutic challenge in the treatment of drug addiction. As with humans, drug-seeking behaviour can be precipitated in laboratory animals by exposure to a small dose of the drug (prime).
Robyn Mary Brown, Jennifer Lynn Short, Andrew John Lawrence   +2 more
doaj   +1 more source

Impact of Perineuronal Net Removal in the Rat Medial Prefrontal Cortex on Parvalbumin Interneurons After Reinstatement of Cocaine Conditioned Place Preference

Frontiers in Cellular Neuroscience, 2022
Parvalbumin (PV)-positive cells are GABAergic fast-spiking interneurons that modulate the activity of pyramidal neurons in the medial prefrontal cortex (mPFC) and their output to brain areas associated with learning and memory.
Angela E. Gonzalez, Angela E. Gonzalez, Emily T. Jorgensen, Jonathan D. Ramos, John H. Harkness, Jake A. Aadland, Travis E. Brown, Barbara A. Sorg, Barbara A. Sorg   +8 more
doaj   +1 more source