Results 41 to 50 of about 26,009 (298)

Ranking the contribution of behavioral measures comprising oxycodone self-administration to reinstatement of drug-seeking in male and female rats

open access: yesFrontiers in Behavioral Neuroscience, 2022
IntroductionRates of relapse to drug use during abstinence are among the highest for opioid use disorder (OUD). In preclinical studies, reinstatement to drug-seeking has been extensively studied as a model of relapse–but the work has been primarily in ...
Suman K. Guha   +8 more
doaj   +1 more source

Reinstating the Novelty P3 [PDF]

open access: yesScientific Reports, 2016
AbstractP300 (or P3) is a major positive complex in the human event-related potential, occurring some 300 ms after stimulus onset and long thought to be the cortical correlate of the Orienting Reflex, our automatic attention-grabbing response to a novel stimulus.
Barry, Robert J.   +2 more
openaire   +3 more sources

Cefazolin and ceftriaxone attenuate the cue-primed reinstatement of alcohol-seeking

open access: yesFrontiers in Pharmacology, 2015
Alcohol consumption and the reinstatement of alcohol-seeking rely on glutamate and GABA transmission. Modulating these neurotransmitters may be a viable treatment strategy to prevent alcohol relapse. N-acetylcysteine (NAC) and the antibiotic ceftriaxone
Ana eWeiland   +2 more
doaj   +1 more source

On the Issue of Reinstatement in Argumentation [PDF]

open access: yes, 2006
Dung's theory of abstract argumentation frameworks [1] led to the formalization of various argument-based semantics, which are actually particular forms of dealing with the issue of reinstatement. In this paper, we re-examine the issue of semantics from the perspective of postulates.
openaire   +4 more sources

7,8-Dihydroxyflavone Enhances Cue-Conditioned Alcohol Reinstatement in Rats

open access: yesBrain Sciences, 2020
Alcohol use disorder (AUD) is a detrimental disease that develops through chronic ethanol exposure. Reduced brain-derived neurotrophic factor (BDNF) expression has been associated with AUD and alcohol addiction, however the effects of activation of BDNF ...
Samuel J. Hogarth   +2 more
doaj   +1 more source

Reinstating the National Guidelines of State Policy within Indonesia's Presidential System: Exploring the Possibilities

open access: yesFiat Justisia, 2023
Placing the National Guidelines of State Policy (GBHN or PPHN) developed by the People's Consultative Assembly (MPR) as a guiding framework for the President could elevate the MPR above the President, a model practiced in Indonesia from 1945 to 1999 ...
Muhtadi Muhtadi, Zulkarnain Ridlwan
doaj   +1 more source

Morphine pre-exposure facilitates reinstatement but attenuates retention of morphine-induced place preference [PDF]

open access: yes, 2010
BACKGROUND: Drug-associated conditioned stimuli are a key factor to induce morphine relapse. To date, limited evidence is available regarding the impact of drug history on propensity or vulnerability to relapse after long-term abstinence.
Yang, Xiaoyan   +4 more
core   +1 more source

Methanolic extract of Morinda citrifolia L. (noni) unripe fruit attenuates ethanol-induced conditioned place preferences in mice

open access: yesFrontiers in Pharmacology, 2016
Phytotherapy is an emerging field successfully utilized to treat various chronic diseases including alcohol dependence. In the present study, we examined the effect of the standardized methanolic extract of Morinda citrifolia Linn. unripe fruit (MMC), on
Yasmin Khan, Vijayapandi Pandy
doaj   +1 more source

Alternative use of suvorexant (Belsomra®) for the prevention of alcohol drinking and seeking in rats with a history of alcohol dependence

open access: yesFrontiers in Behavioral Neuroscience, 2022
Alcohol use disorder (AUD) is one of the most treatment-resistant medical conditions globally. The orexin (Orx) system regulates diverse physiological processes, including stress, and is a system of interest for the development of pharmaceuticals to ...
Francisco J. Flores-Ramirez   +5 more
doaj   +1 more source

Experimental boundary conditions of reinstatement induced return of fear in humans: Is reinstatement in humans what we think it is?

open access: yes, 2022
Experimental paradigms used to study reinstatement of fear in humans are characterized by procedural heterogeneity. Reinstatement protocols involve unexpected (re)-presentations of the unconditioned stimulus (USs) after fear extinction training. Here, we
Tina Lonsdorf, Rachel Sjouwerman
core   +1 more source

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