Results 41 to 50 of about 26,009 (298)
IntroductionRates of relapse to drug use during abstinence are among the highest for opioid use disorder (OUD). In preclinical studies, reinstatement to drug-seeking has been extensively studied as a model of relapse–but the work has been primarily in ...
Suman K. Guha +8 more
doaj +1 more source
Reinstating the Novelty P3 [PDF]
AbstractP300 (or P3) is a major positive complex in the human event-related potential, occurring some 300 ms after stimulus onset and long thought to be the cortical correlate of the Orienting Reflex, our automatic attention-grabbing response to a novel stimulus.
Barry, Robert J. +2 more
openaire +3 more sources
Cefazolin and ceftriaxone attenuate the cue-primed reinstatement of alcohol-seeking
Alcohol consumption and the reinstatement of alcohol-seeking rely on glutamate and GABA transmission. Modulating these neurotransmitters may be a viable treatment strategy to prevent alcohol relapse. N-acetylcysteine (NAC) and the antibiotic ceftriaxone
Ana eWeiland +2 more
doaj +1 more source
On the Issue of Reinstatement in Argumentation [PDF]
Dung's theory of abstract argumentation frameworks [1] led to the formalization of various argument-based semantics, which are actually particular forms of dealing with the issue of reinstatement. In this paper, we re-examine the issue of semantics from the perspective of postulates.
openaire +4 more sources
7,8-Dihydroxyflavone Enhances Cue-Conditioned Alcohol Reinstatement in Rats
Alcohol use disorder (AUD) is a detrimental disease that develops through chronic ethanol exposure. Reduced brain-derived neurotrophic factor (BDNF) expression has been associated with AUD and alcohol addiction, however the effects of activation of BDNF ...
Samuel J. Hogarth +2 more
doaj +1 more source
Placing the National Guidelines of State Policy (GBHN or PPHN) developed by the People's Consultative Assembly (MPR) as a guiding framework for the President could elevate the MPR above the President, a model practiced in Indonesia from 1945 to 1999 ...
Muhtadi Muhtadi, Zulkarnain Ridlwan
doaj +1 more source
Morphine pre-exposure facilitates reinstatement but attenuates retention of morphine-induced place preference [PDF]
BACKGROUND: Drug-associated conditioned stimuli are a key factor to induce morphine relapse. To date, limited evidence is available regarding the impact of drug history on propensity or vulnerability to relapse after long-term abstinence.
Yang, Xiaoyan +4 more
core +1 more source
Phytotherapy is an emerging field successfully utilized to treat various chronic diseases including alcohol dependence. In the present study, we examined the effect of the standardized methanolic extract of Morinda citrifolia Linn. unripe fruit (MMC), on
Yasmin Khan, Vijayapandi Pandy
doaj +1 more source
Alcohol use disorder (AUD) is one of the most treatment-resistant medical conditions globally. The orexin (Orx) system regulates diverse physiological processes, including stress, and is a system of interest for the development of pharmaceuticals to ...
Francisco J. Flores-Ramirez +5 more
doaj +1 more source
Experimental paradigms used to study reinstatement of fear in humans are characterized by procedural heterogeneity. Reinstatement protocols involve unexpected (re)-presentations of the unconditioned stimulus (USs) after fear extinction training. Here, we
Tina Lonsdorf, Rachel Sjouwerman
core +1 more source

