Glutamate and reinstatement [PDF]
The importance of glutamate in the reinstatement of cocaine-seeking behavior has been established. New molecular and neurochemical adaptations in the glutamatergic system which drive cocaine relapse have been identified, such as the ability of CB1 receptor stimulation to reduce basal glutamate levels and the involvement of the GluR1 receptor subunit in
Lori A, Knackstedt, Peter W, Kalivas
openaire +2 more sources
Identification of brain nuclei implicated in cocaine-primed reinstatement of conditioned place preference: a behaviour dissociable from sensitization. [PDF]
Relapse prevention represents the primary therapeutic challenge in the treatment of drug addiction. As with humans, drug-seeking behaviour can be precipitated in laboratory animals by exposure to a small dose of the drug (prime).
Robyn Mary Brown +2 more
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Parvalbumin (PV)-positive cells are GABAergic fast-spiking interneurons that modulate the activity of pyramidal neurons in the medial prefrontal cortex (mPFC) and their output to brain areas associated with learning and memory.
Angela E. Gonzalez +8 more
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A high percentage of relapse to compulsive cocaine-taking and cocaine-seeking behaviors following abstinence constitutes a major obstacle to the clinical treatment of cocaine addiction.
Changliang Zhu +19 more
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Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we assessed whether co-consumption of oxycodone and alcohol influence the intake of one another, demand for oxycodone, and the neurocircuitry underlying cue-primed ...
Courtney S. Wilkinson +7 more
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Supporting older eyewitnesses’ episodic memory: the self-administered interview and sketch reinstatement of context [PDF]
Environmental support at retrieval improves episodic performance, yet there exists very few empirically evaluated techniques for supporting older witnesses/victims’ remembering (> 65years).
Dando, Coral +6 more
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Stronger memory representation after memory reinstatement during retrieval in the human hippocampus
Memory retrieval allows us to reinstate previously encoded information but is also considered to contribute to memory enhancement. Retrieval-induced enhancement may involve processing to strengthen memory traces, but neural processing beyond ...
Joonyoung Kang +2 more
doaj +1 more source
Impact of tobacco smoke constituents on nicotine-seeking behavior in adolescent and adult male rats
IntroductionGiven the rapid increase in teen vaping over recent years it is critical to understand mechanisms underlying addiction and relapse to tobacco use at this age.
Candice A. Gellner +3 more
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Inactivation of the nucleus accumbens core or medial shell attenuates reinstatement of sugar-seeking behavior following sugar priming or exposure to food-associated cues. [PDF]
Re-exposure to either palatable food or to conditioned stimuli associated with food is known to reinstate food-seeking after periods of abstinence.
Peagan Lin, Wayne E Pratt
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A principles-based approach to cadastral reinstatement for Australian jurisdictions [PDF]
Cadastral reinstatement is the process whereby a cadastral surveyor re-establishes and describes the position of boundaries created by earlier actions. Previous boundary reinstatement cases are examined and the principles on which the courts made their ...
Campbell, G., G. Campbell
core +1 more source

