Results 21 to 30 of about 26,009 (298)

Glutamate and reinstatement [PDF]

open access: yesCurrent Opinion in Pharmacology, 2009
The importance of glutamate in the reinstatement of cocaine-seeking behavior has been established. New molecular and neurochemical adaptations in the glutamatergic system which drive cocaine relapse have been identified, such as the ability of CB1 receptor stimulation to reduce basal glutamate levels and the involvement of the GluR1 receptor subunit in
Lori A, Knackstedt, Peter W, Kalivas
openaire   +2 more sources

Identification of brain nuclei implicated in cocaine-primed reinstatement of conditioned place preference: a behaviour dissociable from sensitization. [PDF]

open access: yesPLoS ONE, 2010
Relapse prevention represents the primary therapeutic challenge in the treatment of drug addiction. As with humans, drug-seeking behaviour can be precipitated in laboratory animals by exposure to a small dose of the drug (prime).
Robyn Mary Brown   +2 more
doaj   +1 more source

Impact of Perineuronal Net Removal in the Rat Medial Prefrontal Cortex on Parvalbumin Interneurons After Reinstatement of Cocaine Conditioned Place Preference

open access: yesFrontiers in Cellular Neuroscience, 2022
Parvalbumin (PV)-positive cells are GABAergic fast-spiking interneurons that modulate the activity of pyramidal neurons in the medial prefrontal cortex (mPFC) and their output to brain areas associated with learning and memory.
Angela E. Gonzalez   +8 more
doaj   +1 more source

Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Reinstatement of Cocaine-Mediated Conditioned Place Preference in Mice

open access: yesFrontiers in Behavioral Neuroscience, 2022
A high percentage of relapse to compulsive cocaine-taking and cocaine-seeking behaviors following abstinence constitutes a major obstacle to the clinical treatment of cocaine addiction.
Changliang Zhu   +19 more
doaj   +1 more source

Voluntary alcohol intake alters the motivation to seek intravenous oxycodone and neuronal activation during the reinstatement of oxycodone and sucrose seeking

open access: yesScientific Reports, 2023
Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we assessed whether co-consumption of oxycodone and alcohol influence the intake of one another, demand for oxycodone, and the neurocircuitry underlying cue-primed ...
Courtney S. Wilkinson   +7 more
doaj   +1 more source

Supporting older eyewitnesses’ episodic memory: the self-administered interview and sketch reinstatement of context [PDF]

open access: yes, 2020
Environmental support at retrieval improves episodic performance, yet there exists very few empirically evaluated techniques for supporting older witnesses/victims’ remembering (> 65years).
Dando, Coral   +6 more
core   +1 more source

Stronger memory representation after memory reinstatement during retrieval in the human hippocampus

open access: yesNeuroImage, 2022
Memory retrieval allows us to reinstate previously encoded information but is also considered to contribute to memory enhancement. Retrieval-induced enhancement may involve processing to strengthen memory traces, but neural processing beyond ...
Joonyoung Kang   +2 more
doaj   +1 more source

Impact of tobacco smoke constituents on nicotine-seeking behavior in adolescent and adult male rats

open access: yesFrontiers in Psychiatry, 2023
IntroductionGiven the rapid increase in teen vaping over recent years it is critical to understand mechanisms underlying addiction and relapse to tobacco use at this age.
Candice A. Gellner   +3 more
doaj   +1 more source

Inactivation of the nucleus accumbens core or medial shell attenuates reinstatement of sugar-seeking behavior following sugar priming or exposure to food-associated cues. [PDF]

open access: yesPLoS ONE, 2014
Re-exposure to either palatable food or to conditioned stimuli associated with food is known to reinstate food-seeking after periods of abstinence.
Peagan Lin, Wayne E Pratt
doaj   +1 more source

A principles-based approach to cadastral reinstatement for Australian jurisdictions [PDF]

open access: yes, 2011
Cadastral reinstatement is the process whereby a cadastral surveyor re-establishes and describes the position of boundaries created by earlier actions. Previous boundary reinstatement cases are examined and the principles on which the courts made their ...
Campbell, G., G. Campbell
core   +1 more source

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