Results 21 to 30 of about 106,778 (281)
Cannabinoid Receptor Involvement in Stress-Induced Cocaine Reinstatement: Potential Interaction with Noradrenergic Pathways [PDF]
, 2012 This study examined the role of endocannabinoid signaling in stress-induced reinstatement of cocaine seeking and explored the interaction between noradrenergic and endocannabinergic systems in the process.
Hillard, Cecilia J. +6 more
core +2 more sources
Brain Sciences, 2012 Reinstatement of conditioned place preferences have been used to investigate physiological mechanisms mediating drug-seeking behavior in adolescent and adult rodents; however, it is still unclear how psychostimulant exposure during adolescence affects ...
Kimberly A. Badanich, Cheryl L. Kirstein
doaj +1 more source
Self-Administration of Toluene Vapor in Rats
Frontiers in Neuroscience, 2020 Inhalants, including volatile organic solvents such as toluene, continue to be one of the most prevalent, and often first substances abused by adolescents.
Kevin M. Braunscheidel +3 more
doaj +1 more source
Glutamate and reinstatement [PDF]
Current Opinion in Pharmacology, 2009 The importance of glutamate in the reinstatement of cocaine-seeking behavior has been established. New molecular and neurochemical adaptations in the glutamatergic system which drive cocaine relapse have been identified, such as the ability of CB1 receptor stimulation to reduce basal glutamate levels and the involvement of the GluR1 receptor subunit in
Lori A, Knackstedt, Peter W, Kalivas
openaire +2 more sources
Prefrontal dopamine regulates fear reinstatement through the downregulation of extinction circuits
eLife, 2015 Prevention of relapses is a major challenge in treating anxiety disorders. Fear reinstatement can cause relapse in spite of successful fear reduction through extinction-based exposure therapy.
Natsuko Hitora-Imamura +5 more
doaj +1 more source
Stronger memory representation after memory reinstatement during retrieval in the human hippocampus
NeuroImage, 2022 Memory retrieval allows us to reinstate previously encoded information but is also considered to contribute to memory enhancement. Retrieval-induced enhancement may involve processing to strengthen memory traces, but neural processing beyond ...
Joonyoung Kang +2 more
doaj +1 more source
Gradual extinction reduces reinstatement [PDF]
Frontiers in Behavioral Neuroscience, 2015 The current study investigated whether gradually reducing the frequency of aversive stimuli during extinction can prevent the return of fear. Thirty-one participants of a three-stage procedure (acquisition, extinction and a reinstatement test on day 2) were randomly assigned to a standard extinction (SE) and gradual extinction (GE) procedure.
Shiban, Youssef +3 more
openaire +4 more sources
The Effectiveness of Reinstatement as a Public Policy Remedy: The Kohler Case [PDF]
, 1969 This article is concerned with two aspects of the NLRB reinstatement remedy as applied in the famous Kohler case: (1) how effective the remedy was, particularly in terms of the number of employees who returned to Kohler under its protection, and (2) what
Drotning, John E, Lipsky, David B
core +3 more sources
Reinstatement of extinguished fear by an unextinguished conditional stimulus
Frontiers in Behavioral Neuroscience, 2012 Anxiety disorders are often treated using extinction-based exposure therapy, but relapse is common and can occur as a result of reinstatement, whereby an aversive trigger can reinstate extinguished fear. Animal models of reinstatement commonly utilize a
Lindsay R Halladay +4 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2022 IntroductionRates of relapse to drug use during abstinence are among the highest for opioid use disorder (OUD). In preclinical studies, reinstatement to drug-seeking has been extensively studied as a model of relapse–but the work has been primarily in ...
Suman K. Guha +8 more
doaj +1 more source