Results 91 to 100 of about 113,150 (329)
Introduction Melanin, derived from tyrosine, plays a pivotal role in skin pigmentation through melanogenesis. Disruptions in this process lead to hyperpigmentation, a condition affecting skin tone and quality of life.
Russell Wong +6 more
doaj +1 more source
EFFORTS TO REJUVENATE THE PEOPLE'S COCOA IN THE EAST KOLAKA DISTRICT OF INDONESIA [PDF]
The high demand for the world market for cocoa has made the government and people of East Kolaka Regency rejuvenate the cocoa plants that have been managed so far. Plants that are very old and very low in productivity naturally have been rejuvenated into
Salam I., Rosmalah S., Munadi L.O.M.
doaj
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Temperature shifts in the Sinai model: static and dynamical effects
We study analytically and numerically the role of temperature shifts in the simplest model where the energy landscape is explicitely hierarchical, namely the Sinai model.
Aspelmeier T +43 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Modulating the rejuvenation in a Al75Mg25 metallic glass by multiple recovery annealing treatment
Rejuvenation presents a promising way to improve the plasticity of metallic glasses. How modulating the degree of rejuvenation of metallic glasses remains a challenging issue. Here, based on the molecular dynamics simulation, we investigate the evolution
Xuelian Li +6 more
doaj +1 more source
Non-equilibrium aging dynamics in 3D Ising spin glass Cu$_{0.5}$Co$_{0.5}$Cl$_{2}$-FeCl$_{3}$ GBIC has been studied by zero-field cooled (ZFC) magnetization and low frequency AC magnetic susceptibility ($f = 0.05$ Hz), where $T_{g} = 3.92 \pm 0.11$ K ...
Almeida +27 more
core +3 more sources
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
At the heart of the home : An animal reading of mikhail bulgakov's the heart of a dog [PDF]
When we try and contemplate who it is that we think we are in the world history has an important role to play. It can alert us to what we have lost; can point up how we have come to think what we think; and can remind us that what we think now will ...
Fudge, Erica
core
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source

