Results 101 to 110 of about 104,614 (297)

2013 age profile of the academic staff in universities, polytechnics and wānanga [PDF]

The ageing of New Zealand’s academic workforce requires careful management, however, universities now have a larger pool of ‘other’ academic staff from which rejuvenation of the senior academic workforce could occur.
Mieke Wensvoort
core  

On temperature chaos in Ising and XY Spin Glasses

, 2004
We argue that the chaotic temperature effect predicted in Ising spin glasses should be stronger when one considers continuous (XY, Heisenberg) kind of spins, due to bigger entropic fluctuations.
Krzakala, Florent
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Aging and scaling laws in $\beta$-hydroquinone-clathrate

, 2004
The dielectric permittivity of the orientational glass methanol(x=0.73)-$\beta$-hydroquinone-clathrate has been studied as function of temperature and waiting time using different temperature-time-protocols.
A. Bray, A. Kityk, D. Fisher, D. Fisher, D. Fisher, E. Colla, E. Vincent, F. Alberici, F. Alberici, F. Alberici-Kious, F. Alberici-Kious, H. Woll, H. Woll, H. Yoshino, Heiko Rieger, K. Jonason, Klaus Knorr, L. Berthier, L. Cugliandolo, Maikel C. Rheinstädter, P. Jönsson, P. Jönsson, R. Leheny, T. Matsuo   +23 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Neuropsychological and neuroimaging characteristics of patients with mild cognitive impairment and negative-amyloid deposition

Frontiers in Neurology
ObjectivesAccumulating studies have reported that some mild cognitive impairment (MCI) patients without significant β-amyloid (Aβ) deposition on amyloid positron emission tomography (PET) can later develop Alzheimer’s disease (AD).
Xiangwei Dai, Xiangwei Dai, Junying Zhang, Junying Zhang, Xin Li, Xin Li, Yaojing Chen, Yaojing Chen, Yanan Qiao, Shujuan Zhang, Kewei Chen, Lin Ai, Dantao Peng, Zhanjun Zhang, Zhanjun Zhang, Zhanjun Zhang   +15 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Application of facial analysis in facial rejuvenation

Pifu-xingbing zhenliaoxue zazhi
Correct facial analysis is the first step to achieve good results in any facial plastic surgery or facial rejuvenation surgery/procedure. Assessing the corresponding anatomic area of facial aging through facial analysis and precisely designing the ...
Chen ZHONG, Shengyuan JIN, Chunhua JIN
doaj   +1 more source