Results 41 to 50 of about 103,312 (279)

Aging and Rejuvenation with Fractional Derivatives [PDF]

, 2004
We discuss a dynamic procedure that makes the fractional derivatives emerge in the time asymptotic limit of non-Poisson processes. We find that two-state fluctuations, with an inverse power-law distribution of waiting times, finite first moment and ...
B. J. West, Bruce J. West, D. Bedeaux, E. W. Montroll, F. Bardou, Gerardo Aquino, Mauro Bologna, Paolo Grigolini, R. Kubo   +8 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Shannon Entropy of Gray Matter Eigenmodes: A Novel Biomarker for Alzheimer's Disease and Heterogeneous MCI Trajectories

Advanced Science
Current Alzheimer's disease (AD) diagnostics rely on late‐stage cognitive assessments or invasive biomarkers. Neuroimaging offers non‐invasive alternatives, but single‐modality approaches (structural atrophy or functional connectivity) face limitations ...
Yumeng Li, Gaoping Long, Xinyue Zhang, Kewei Chen, Xin Li, Zhanjun Zhang   +5 more
doaj   +1 more source

Planning Optimal Rejuvenation Policy for Aging Software Systems via a Two-Layer Model

IEEE Access, 2020
Software rejuvenation is a proactive fault management technique widely used for preventing performance degradation and failures due to software aging.
Jingwei Li, Yong Qi, Guanghua Wang, Jinwei Lin   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Memory effects in response functions of driven vortex matter

, 2001
Vortex flow in driven type II superconductors shows strong memory and history dependent effects. Here, we study a schematic microscopic model of driven vortices to propose a scenario for a broad set of these kind of phenomena ranging from ``rejuvenation''
, , Bassler K. E., Binder K., Bouchaud J. P., Brandt E. H., Cohen L. F., H. Jeldtoft Jensen, Jackson D. K., Lefloch F., M Nicodemi, Nicodemi M., Nicodemi M., Nicodemi M., Schmittmann B.   +14 more
core   +1 more source

Global Facial Rejuvenation Using a New Cohesive, Highly Concentrated Hyaluronic Acid Filler: A Descriptive Analysis of 35 Cases

Cosmetics, 2023
Cosmetic procedures using fillers have gained importance over the last decades due to their ability to offer rejuvenation and beautification quickly with no (or minor) side effects. Hyaluronic acid (HA) gel is the most used filler in cosmetic dermatology;
Maria Claudia Almeida Issa, Andreia Fogaça, Eliandre Palermo, Luciana Maluf, Patricia Ormiga, Luciana Conrado, Luis Henrique Barbizan de Moura   +6 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source