Results 121 to 130 of about 1,855,106 (245)
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.Irigenin alleviates blue light‐induced RPE cell damage by inhibiting NLRP3 inflammasome and p38/NF‐κB signalling, showing potential for AMD prevention. ABSTRACT Age‐related macular degeneration (AMD), a primary cause of vision loss among older adults, is strongly associated with inflammatory processes.
I‐Li Su +9 more
wiley +1 more source
Transcriptional Adaptations to Muscle Loading in a Murine Model of Achilles Tendinopathy
Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.ABSTRACT Achilles tendinopathy limits mobility and decreases quality of life. Physical therapy (eccentric muscle loading) improves tendon function; however, the underlying mechanisms are unknown. This study investigated the effect of load magnitude and treatment duration in a mouse Achilles tendinopathy model.
Dylan C. Easley +5 more
wiley +1 more source
Case report and literature review: clinical manifestations and treatment of human RelA deficiency
Frontiers in ImmunologyRelA deficiency resulting from mutations in the human RELA gene is a recently identified inborn errors of immunity (IEI). The RELA gene encodes the RelA (p65) protein, one of the five transcription factors of the NF-κB family, which plays a critical role
Chenghao Wang +11 more
doaj +1 more source
High‐Throughput Screen of NPQ in Sorghum Shows Highly Polygenic Architecture of Photoprotection
Plant-Environment Interactions, Volume 7, Issue 1, February 2026.ABSTRACT Natural genetic variation in photosynthesis and photoprotection within crop germplasm represents an untapped resource for crop improvement. Sorghum bicolor (sorghum) is one of the world's most widely grown crops, yet the genetic basis of photoprotection in sorghum is not well understood.
Richard L. Vath +9 more
wiley +1 more source
Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα
eLifeThe canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in pancreatic ductal adenocardinoma (PDAC) tumours.
Francesca Butera +3 more
doaj +1 more source
Practical Benefits of Aspect-Oriented Programming Paradigm in Discrete Event Simulation
Modelling and Simulation in Engineering, 2014 Aspect-oriented modeling and simulation is a new approach which uses the separation of concerns principle to enhance the quality of models and simulation tools. It adopts the separation of concerns (SOC) principle.
Meriem Chibani +2 more
doaj +1 more source
, 2012 Durante el desarrollo de este proyecto final de carrera se aborda la creación e implementación del protocolo ReLA bajo un lenguaje de programación concreto y unificado en un único ejecutable.
openaire +1 more source
Calycosin Targets the CYP1B1‐AKT/SP1‐GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis
Phytotherapy Research, Volume 40, Issue 2, Page 721-736, February 2026.Mechanism of Calycosin in Regulating Ferroptosis in Colorectal Cancer via Binding to CYP1B1. ABSTRACT Calycosin, a natural flavonoid small‐molecule compound derived from traditional Chinese medicine, has demonstrated remarkable pharmacological activity in the field of cancer therapy.
Lihan Bie +9 more
wiley +1 more source
Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging
Aging Cell, Volume 25, Issue 2, February 2026.Aging exacerbates high‐fat diet (HFD) induced hepatic steatosis, and transcriptional dysregulation of pathways including inflammation, immune, and metabolic regulation in mouse liver and hepatocytes. The addition of rapamycin to HFD reversed most HFD‐driven gene‐expression changes in old mice, including those linked to metabolic dysfunction and ...
Aaron Havas +11 more
wiley +1 more source