Results 131 to 140 of about 153,606 (275)
Dietary tannin‐associated molecular programs converge on a TGFA‐centered regulatory axis that governs osteosarcoma progression and immune remodeling. Multi‐omics integration combined with machine learning identifies a tannin‐related risk score (TRR) that stratifies tumor aggressiveness and immune landscape heterogeneity.
Ge Yunling +8 more
wiley +1 more source
Functional analysis of relA and rshA, two relA/spoT homologues of Streptomyces coelicolor A3(2
Deletion of the (p)ppGpp synthetase gene, relA, of Streptomyces coelicolor A3(2) results in loss of production of the antibiotics actinorhodin (Act) and undecylprodigiosin (Red) and delayed morphological differentiation when the mutant is grown under ...
Mervyn Bibb, Andrew Hesketh, Jongho Sun
core
miR-324-3p induced RelA promoter.
A miR-324-3p binding sits is present at nucleotides 45 to 66 upstream to RelA transcription start site (TSS) (A). Three bases (shown in bold) in the miR-324-3p binding site were mutated in the RelA promoter to create a mutant promoter vector (A).
Courtney Pokrzywa (483593) +4 more
core +1 more source
A partir de la conocida descripción heliocéntrica del movimiento planetario se rescata la menos conocida aunque muy útil descripción geocéntrica .Las estaciones del año no sólo dependen de la inclinación del eje: con frecuencia olvidamos la dependencia ...
Agustin Rela
doaj
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
Unsolved accidents in fuel storage tanks : Resolution methodology by mathematical modeling under systemic appproach. [PDF]
Storage of mixtures of heavy hydrocarbon fuels with lighter components is a worldwide necessity because of their use for the construction of roads (asphalt diluted), the energy for industrial production (furnaces, boilers ...
Rela Musiani, Guillermo
core
Characterisation of RELA dynamics in pancreatic ductal adenocarcinoma
The NF-kB transcription factor RELA is a master regulator of the immune response and cell survival. Numerous studies have determined the parameters and configuration of single cell RELA translocation dynamics, with various cell types displaying ...
Butera, F
core
Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang +10 more
wiley +1 more source
(A) Comparison of p65/RelA and its mutant (p65 G170A/P172A/P176A) (p65/RelAm) stability in 293T cells. (B) Comparison of p65/RelAm stability in the presence or absence of proteasome inhibitor MG-132 in 293T cells.
Albert Ha (614051) +5 more
core +1 more source
The mechanisms driving the progression of NAFLD through NASH, cirrhosis and HCC are unclear. In this study, we have comprehensively analyzed multi‐cohort transcriptomics data of the whole NAFLD spectrum to unlock the paradigm changes in gene expression and its regulation.
Anusha Patodia +5 more
wiley +1 more source

