Results 121 to 130 of about 125,603 (234)
Targeting DNA Polymerase Epsilon Induces Tumor Clearance and Activates an NF-κB-Mediated Inflammatory Response in Triple-Negative Breast Cancer. [PDF]
Sher EF +12 more
europepmc +1 more source
ETS1–EGR2 facilitates renal cell carcinoma progression by activating NOTCH signalling
ETS1 expression is significantly higher in ccRCC samples, and ETS1‐overexpression increases RCC cell malignancies in vitro and tumour growth in nude mice. ETS1 binds to EGR2 and destabilises EGR2 protein, which relieves EGR2's inhibitory effect on NOTCH signalling. NOTCH signalling activation promotes RCC development.
Weifeng Ye +6 more
wiley +1 more source
Comprehensive metabolic characterization of pediatric ependymomas. [PDF]
Li T +16 more
europepmc +1 more source
ABSTRACT Multi‐supported non‐structural components (NSCs) are prone to seismic damage, yet their response prediction remains challenging when support motions are spatially incoherent. This study proposes an enhanced quasi‐static condensation (EQSC) method for linear, lightweight, dynamically detuned multi‐supported NSCs under the neglect of primary ...
Duozhi Wang +5 more
wiley +1 more source
Stringent Response Regulates the Persister Formation and Virulence of <i>Vibrio splendidus</i>. [PDF]
Qin M +5 more
europepmc +1 more source
From Observed Damage to Executable Repair Quantities: The RELA Repair Module
Postearthquake workflows currently support three distinct classes of decisions: safety clearance through rapid tagging, portfolio‐level economic damage estimation through probabilistic loss models, and field inspections based on locally defined survey forms, which may subsequently trigger project‐specific strengthening through retrofit design. However,
Zoran Stojadinović +6 more
wiley +1 more source
cJun-assisted loading of RelA DNA-binding promotes synergistic lung epithelial antimicrobial responses. [PDF]
Pantaleón García J +10 more
europepmc +1 more source
The chemical characterization of the LB extract confirmed the presence of polysaccharides and specific small‐molecule constituents (e.g., rutin, isoquercitrin). Network pharmacology analysis predicted that the bioactive components of LB were able to interact with core targets such as TP53, AKT1, and JUN, and molecular docking simulations suggested ...
Ruxin Liu +9 more
wiley +1 more source

