Results 101 to 110 of about 125,603 (234)
A partir de la conocida descripción heliocéntrica del movimiento planetario se rescata la menos conocida aunque muy útil descripción geocéntrica .Las estaciones del año no sólo dependen de la inclinación del eje: con frecuencia olvidamos la dependencia ...
Agustin Rela
doaj
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent form of non‐Hodgkin lymphoma, exhibiting significant molecular and clinical heterogeneity. Advances in classification integrating phenotypic, genetic, and transcriptomic features have improved diagnosis and prognosis.
Marina Pérez‐Aguilera +14 more
wiley +1 more source
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
wiley +1 more source
Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini +4 more
wiley +1 more source
Enhanced Classification System for Real-Time Embedded Vision Applications
Embedded computer vision systems are increasingly being adopted across various domains, playing a pivotal role in enabling advanced technologies such as autonomous vehicles and industrial automation.
Ramzi Khelifi +2 more
doaj +1 more source
Chicoric acid (A) and caftaric acid (B), active components of Echinacea purpurea, increase phosphorylation of NF‑κB p65 (Ser529). These findings indicate that both compounds can modulate immune responses through regulation of NF‑κB signalling, supporting their potential immunomodulatory roles.
Evdokia Thanasi, Yashar Sadigh
wiley +1 more source
RelA, also known as nuclear factor kappa B p65, plays a crucial role in the pathogenesis of various liver diseases. However, the specific role of RelA in hepatocytes during the progression of metabolic dysfunction-associated steatotic liver disease ...
Yihuai He +9 more
doaj +1 more source
Nonlinearities and Switch‐Like Behavior in Gene Expression: From Genetics to Biochemistry and Back
Modest changes in transcription‐factor or chromatin‐regulator dosage can have disproportionate effects when gene‐regulatory systems operate near nonlinear thresholds. Sigmoidal input–output relationships, chromatin and cofactor recruitment, and changes in threshold position or response steepness provide molecular routes by which quantitative dosage ...
Reiner A. Veitia, James A. Birchler
wiley +1 more source
Using an interpretable deep learning framework (CARSS) applied to multi‐tissue single‐cell RNA sequencing, we identify CD34⁺PDGFRα⁺ telocytes (CPTCs) as the primary mechanosensors bridging somatic acupuncture stimulation and visceral repair. Mechanical force at acupoints activates an AP‐1/Hsp70 immediate‐early gene program in fascial CPTCs, triggering ...
Haixiang Huang +12 more
wiley +1 more source

