Results 101 to 110 of about 153,606 (275)

Química y simetrias

open access: yes, 2009
Editorial por Agustín Rela (pág 3)La forma hace a la función por Alberto Ghini y Cecilia Di Risio (pág 5)Problemas matemáticos: ¡Guarda con el triángulo!
Rela, Agustín   +4 more
core  

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window

open access: yesNeurobiology of Disease, 2013
Nuclear factor-kappaB (NF-κB) p50/RelA is a key molecule with a dual effect in the progression of ischemic stroke. In harmful ischemia, but not in preconditioning insult, neurotoxic activation of p50/RelA is characterized by RelA-specific acetylation at ...
Annamaria Lanzillotta   +8 more
doaj   +1 more source

Effects of Common Food Additives Kappa‐, Iota‐ and Lambda‐Carrageenans on Intestinal Epithelial Cell Activation and Barrier Disruption

open access: yesClinical &Experimental Allergy, EarlyView.
Carrageenans, widely used food additives, disrupted intestinal epithelial integrity in a gut‐on‐a‐chip model. All types (κ‐, ɩ‐, λ‐) induced cytotoxicity, inflammation and tight junction (TJ) disruption, triggering TNF‐mediated immune responses. λ‐Carrageenan had the most severe effects, supporting the Epithelial Barrier Theory linking food additives ...
Na Sun   +13 more
wiley   +1 more source

Perspectives, aspirations and perceived support students with low economic and cultural capital in the university in Spain and Dominican Republic

open access: yes
This paper investigates the characteristics and both material and emotional costs of upward social mobility through university education in Spain and the Dominican Republic.
Tenorio Rodríguez, María   +2 more
core   +1 more source

RNA helicase p68 deploys β-catenin in regulating RelA/p65 gene expression: implications in colon cancer

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background RelA/p65 a crucial member of NF-κB signaling pathway plays diverse role in mediating oncogenesis. Limited knowledge prevails on the mechanistic insights of RelA gene regulation.
Veenita Khare   +4 more
doaj   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

open access: yesCell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo   +5 more
wiley   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

open access: yesCytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu   +3 more
wiley   +1 more source

Dimerization of the RelA protein ofEscherichia coli

open access: yes, 2001
The RelA protein of Escherichia coli is a ribosome-associated (p)ppGpp synthetase that is activated by amino acid deprivation. It was recently reported that the activity of RelA is regulated by oligomerization mediated by the C-terminal domain of RelA ...
Edward E Ishiguro, Xiaoming Yang
core   +1 more source

Women in business: Gender and commercial space in nineteenth‐century Glasgow

open access: yesThe Economic History Review, EarlyView.
Abstract Focusing on women entrepreneurs in a large British city, we examine how women's commercially listed businesses populated that city. Using commercial property rental records, our study allows us to understand sectoral variation and the distribution of businesses across the city and to assess both the absolute and relative contribution of women ...
Graeme Acheson   +2 more
wiley   +1 more source

RelA-Induced Interferon Response Negatively Regulates Proliferation.

open access: yes, 2015
Both oncogenic and tumor-suppressor activities are attributed to the Nuclear Factor kappa B (NF-kB) pathway. Moreover, NF-kB may positively or negatively regulate proliferation.
Koraljka Rajkovic-Molek (812656)   +29 more
core   +1 more source

Home - About - Disclaimer - Privacy