Results 141 to 150 of about 125,603 (234)

Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-κB signaling in pancreatic cancer. [PDF]

Cell Death Discov
Aggrey-Fynn JE, Busch J, Saul D, Rajput A, Willecke K, Manjunath M, Klimt N, Rajendran K, Schacherer N, Ge W, Thiel J, Abdelrahman A, Truty MJ, Dong M, Johnsen SA.   +14 more
europepmc   +1 more source

Triphala Targets the SLC7A11–GSH–GPX4 Axis to Trigger Ferroptosis in Oral Cancer: An Integrated Network Pharmacology, Molecular Docking, and Experimental Validation Study

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Triphala targets ferroptosis‐related pathways in oral cancer through multi‐compound, multi‐target interactions identified by network pharmacology and molecular docking. In CAL‐27 cells, Triphala suppresses the GPX4/SLC7A11 axis, promotes iron accumulation and lipid peroxidation, and supports an eight‐gene prognostic signature.
Yiwei Zhao, Simin Li, Linxin Jiang, Deborah Kreher, Gerhard Schmalz, Andreas Fichter, Xianda Hu   +6 more
wiley   +1 more source

Single-cell transcriptomics identify mechanical-memory-associated cell states in metastatic HR⁺ breast cancer. [PDF]

Breast Cancer Res
Zhao X, Fan Y, Yang J, Gao H.
europepmc   +1 more source

Gut‐Derived Sodium Butyrate Attenuates Liver Fibrosis by Inhibiting Aerobic Glycolysis via the HDAC3/c‐Myc Signaling Axis

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
This study explores the molecular mechanisms by which NaB ameliorates liver fibrosis from the perspectives of the gut–liver axis and metabolic reprogramming. In vivo and in vitro experiments demonstrate that gut‐derived NaB may alleviate liver injury and fibrosis by inhibiting hepatic stellate cell activation and aerobic glycolysis through the HDAC3/c ...
Yong Sun, Huayue Wu, Yutong Zhou, Pengsheng Yin, Long Wu, Haiyang Li, Shi Zuo, Zhe Yang, Kun Cao   +8 more
wiley   +1 more source

Quercetin attenuates skin inflammation and fibrosis in systemic sclerosis by targeting the RELA/c-Jun axis to suppress th17 cell responses. [PDF]

Front Immunol
Kong X, Leong H, Du M, Yang J, Lai J, Dong Z, Hu M, Gu Y, Li Y, Tan Q, Chu H, Liu Q, Ma Y, Xu W, Li S, Chen Y, Chen D, Chen Y, Lu W, Zhu J, Wang J, Wang L.   +21 more
europepmc   +1 more source

RELA as a Diagnostic Biomarker for Parkinson's Disease by Integrating Ferroptosis, Lipid Metabolism, and Neuroinflammation. [PDF]

Inflammation
Chen Q, Jing Y, Bu W, Zhang J, Liu W, Shi C, Liu C, Su D.   +7 more
europepmc   +1 more source

Endoscopic nipple-sparing mastectomy with immediate DIEP flap reconstruction following neoadjuvant chemotherapy for multifocal HER2-positive breast cancer: a case report. [PDF]

J Surg Case Rep
Mathan PJ, Gandhirajan K, Bose JC, Arumugam S, Manivasagam P, Kamaldeen S.   +5 more
europepmc   +1 more source

Case Report: Diverse pediatric phenotypes of <i>RELA</i> frameshift variants: comparison of two cases. [PDF]

Front Immunol
Hou L, Yin L, Zhao C, Du Y.
europepmc   +1 more source

RelA Signaling in <i>Scgb1a1+</i> Progenitors Mediates Lower Airway Epithelial Atypia in RSV-Induced Post-Viral Lung Disease. [PDF]

Int J Mol Sci
Skibba M, Brasier AR.
europepmc   +1 more source

Ependymoma, RELA Fusion-Positive [PDF]

, 2020
openaire   +1 more source