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A comparison of mechanism‐inspired models for particle relative biological effectiveness (RBE)
Medical Physics, 2018Background and SignificanceThe application of heavy ion beams in cancer therapy must account for the increasing relative biological effectiveness (RBE) with increasing penetration depth when determining dose prescriptions and organ at risk (OAR) constraints in treatment planning.
Robert D, Stewart +5 more
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Relative biological effectiveness (RBE) of 30 MeV electrons at varying depths in tissue
The British Journal of Radiology, 1974Abstract Using the stunting of vertebral growth of one-week-old inbred WHT/Ht mice as the biological test material and Fricke's ferrous sulphate method for dose measurements, the biological effectiveness of 30 MeV electrons relative to 250 kVp X rays has been found to be in the region of 0·82. No difference of statistical significance has been observed
D P, Huang +3 more
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International Journal of Radiation Biology, 2007
Northern peoples can receive elevated radiation doses (1- 10 mSv/y) from transfer of polonium-210 (210Po) through the lichen-caribou-human food chain. Ingested 210Po is primarily blood-borne and thus many of its short range alpha particles irradiate the endothelial cells lining the blood vessels.
Patricia, Thomas +6 more
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Northern peoples can receive elevated radiation doses (1- 10 mSv/y) from transfer of polonium-210 (210Po) through the lichen-caribou-human food chain. Ingested 210Po is primarily blood-borne and thus many of its short range alpha particles irradiate the endothelial cells lining the blood vessels.
Patricia, Thomas +6 more
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Radiation Research, 1971
Neutron doses at 0.43 MeV and at a lower average energy level were plotted against x-ray doses required to produce equal effects in various frequencies of response for eight somatic aberrations found in Tradescantia stamen hairs. Such plots serve as a useful graphic method for expressing RBE values which change as a function of absorbed dose.
A G, Underbrink, A H, Sparrow
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Neutron doses at 0.43 MeV and at a lower average energy level were plotted against x-ray doses required to produce equal effects in various frequencies of response for eight somatic aberrations found in Tradescantia stamen hairs. Such plots serve as a useful graphic method for expressing RBE values which change as a function of absorbed dose.
A G, Underbrink, A H, Sparrow
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Physics in Medicine and Biology, 1987
A new model is applied to bacteria exposed to tritiated water. In this model, the relation between the radiation quality, induction of single- and double-strand breaks in DNA and their repair in vivo can be reasonably described in terms of the microdosimetric distribution and the modification factors for single- and double-strand breaks in DNA.
S, Iwanami, N, Oda
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A new model is applied to bacteria exposed to tritiated water. In this model, the relation between the radiation quality, induction of single- and double-strand breaks in DNA and their repair in vivo can be reasonably described in terms of the microdosimetric distribution and the modification factors for single- and double-strand breaks in DNA.
S, Iwanami, N, Oda
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Health Physics, 1996
The value of the RBE of a test radiation is conventionally determined against a known standard radiation for a chosen response of a selected biological tissue and is expressed as the ratio of tissue absorbed doses at equal effect, or as ratio of magnitudes of the effect at equal absorbed dose.
L E, Feinendegen +2 more
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The value of the RBE of a test radiation is conventionally determined against a known standard radiation for a chosen response of a selected biological tissue and is expressed as the ratio of tissue absorbed doses at equal effect, or as ratio of magnitudes of the effect at equal absorbed dose.
L E, Feinendegen +2 more
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Relative biological effectiveness (RBE) of 50 MV (Be) neutrons for acute and late skin injury
International Journal of Radiation Oncology*Biology*Physics, 1978Abstract Fractionated doses of E d = 50 MeV (D-Be) neutrons and γ-rays were delivered to areas of pigs' skin. Acute response was measured in terms of desquamation, and late (several months) response as degree of contraction relative to control areas.
H R, Withers +4 more
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International Journal of Radiation Oncology*Biology*Physics, 2000
This study aims at providing relative biological effectiveness (RBE) data under reference conditions accounting for the determination of the "clinical RBE" of protons.RBE (ref. (60)Co gamma-rays) of the 200 MeV clinical proton beam produced at the National Accelerator Centre (South Africa) was determined for lung tolerance assessed by survival after ...
Gueulette J. +11 more
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This study aims at providing relative biological effectiveness (RBE) data under reference conditions accounting for the determination of the "clinical RBE" of protons.RBE (ref. (60)Co gamma-rays) of the 200 MeV clinical proton beam produced at the National Accelerator Centre (South Africa) was determined for lung tolerance assessed by survival after ...
Gueulette J. +11 more
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Treatment planning for light ions: How to take into account Relative Biological Effectivness (RBE)
Strahlentherapie und Onkologie, 1999A new treatment planning program was developed for the heavy ion therapy facility at GSI, which is tailored to the special needs for an active beam delivery using a magnetic raster scanner. It also includes a biological model for the estimation of biological effective dose for carbon ions and realizes a fully biological treatment planning.
O, Jäkel +4 more
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[Relative biological effectiveness (RBE) of low-dose californium-252].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1982Relative biological effectiveness (RBE) of 252Cf, with respect to 192Ir, has been determined at the low dose rates commonly used in interstitial and intracavitary therapy. The biological criterion was growth reduction in Vicia faba bean roots. Two varieties of Vicia faba were used.
J, Van Dam +3 more
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