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Relative dose intensity of taxane-based chemotherapy in breast cancer patients in a tertiary hospital

Journal of Oncology Pharmacy Practice, 2023
Introduction Breast cancer (BC) is the most diagnosed tumor among women worldwide. The aim of this study was to investigate the incidence and causes of low relative dose intensity (RDI) < 85% for taxane-based chemotherapy regimens used in the treatment of BC in Sultan Qaboos University Hospital (SQUH).
Amira M Helwani   +3 more
openaire   +2 more sources

[Relative dose intensity of FOLFOX4 regimen].

Gan to kagaku ryoho. Cancer & chemotherapy, 2008
Oxaliplatin (L-OHP) is one of the key drugs against advanced, recurrent colorectal cancer, and FOLFOX4 regimen combination of l-leucovorin (l-LV)and 5-fluorouracil (5-FU)with oxaliplatin is a standard therapy in colorectal cancer. We performed a retrospective study that researched adverse events and relative dose intensity(RDI)to evaluate safety and ...
Daigo, Shouji   +11 more
openaire   +1 more source

Impact of relative dose intensity on the outcome of metastatic colorectal cancer.

Journal of Clinical Oncology, 2013
508 Background: Relative dose intensity (RDI) is the ratio of delivered dose intensity of chemotherapy to standard dose intensity. There is established evidence supporting the significance of RDI in patients with various cancer, however data in patients with metastatic colorectal cancer (mCRC) are limited.
Goro Nakayama   +8 more
openaire   +1 more source

Absolute versus relative intensity of physical activity in a dose-response context

Medicine and Science in Sports and Exercise, 2001
To examine the importance of relative versus absolute intensities of physical activity in the context of population health.A standard computer-search of the literature was supplemented by review of extensive personal files.Consensus reports (Category D Evidence) have commonly recommended moderate rather than hard physical activity in the context of ...
openaire   +2 more sources

FOLFOX4 relative dose intensity and factors associated with dose reduction or stop: A cohort study.

Journal of Clinical Oncology, 2011
e19668 Background: Randomized controlled trials suggest similar efficacy and tolerance of chemotherapy in elderly cancer patients compared to younger.
F. Canoui-Poitrine   +9 more
openaire   +1 more source

Adjuvant chemotherapy for breast cancer – prognostic impact of relative dose-intensity.

Cancer Research, 2009
Abstract Abstract #4109 Introduction: Maintenance of adequate dose intensity (DI) is an important aim in the use of adjuvant chemotherapy for early breast cancer. Some studies report a decreased survival, if the DI is below 80% of the planned dose.
S Kahlert   +5 more
openaire   +1 more source

Improving the Relative Dose Intensity of Systemic Chemotherapy in a Community-Based Outpatient Cancer Center

Journal of Oncology Practice, 2013
Improvements in relative dose intensity were demonstrated in a community-based cancer center through staff education, adherence to existing policies, and development of a febrile neutropenia risk assessment tool.
Kari L, Vavra   +4 more
openaire   +2 more sources

[Dose intensity in cancer chemotherapy: definition, average relative dose intensity and effective dose intensity].

Bulletin du cancer, 1995
The cytotoxic activity of cancer chemotherapy is related to the dose and to the amount of drug delivered per time unit. The significance of time in the effectiveness of a treatment program is frequently overlooked. The term of dose intensity (DI) is used to define the drug dose delivered per time unit and is expressed as mg/m2 per week.
openaire   +1 more source

Effects of a holistic, patient-centered approach on breast cancer relative dose intensity

Advances in Integrative Medicine, 2019
Abstract Purpose A critical component of breast cancer (BC) chemotherapy effectiveness is relative dose intensity (RDI), as Methods The medical records of 161 BC patients (M = 61.5 years, SD = 12.7) from a holistic cancer clinic were collected and analyzed.
Rebecca Louison   +3 more
openaire   +1 more source

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