Results 71 to 80 of about 2,509 (238)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Lost Melody Phenomenon [PDF]
, 2015 A typical phenomenon for machine models of transfinite computations is the existence of so-called lost melodies, i.e. real numbers $x$ such that the characteristic function of the set $\{x\}$ is computable while $x$ itself is not (a real having the first
Carl, Merlin
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Correspondence in OT syntax and minimal link effects [PDF]
, 2004 The aim of this paper is the exploration of an optimality theoretic architecture for syntax that is guided by the concept of "correspondence": syntax is understood as the mechanism of "translating" underlying representations into a surface form.
Vogel, Ralf
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2014 Selected papers on theoretical and applied linguistics, Vol 20, No 2 (2014): Major Trends in Theoretical and Applied Linguistics 2, Selected Papers from the 20th ISTAL, Thessaloniki 1-3 April ...
Nerantzini, Michaela +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 2015 Sells (1987) のいわゆる「主観表現」に関わる分析に関連し、「伝達源」は同時に「自己」「基準」であり、「自己」は「基準」でありうるが、その逆はないという「ロゴフォリック階層」の概念的基盤をなす含意関係について考察し、本稿の分析ではこの現象が下位の視点投射が上位の視点投射の位置へ主要部移動し、それによって上位の視点投射の指定部にあるpro の指標が下位の視点投射指定部のpro に受け継がれることによって捉えられることを提示する。問題の主要部移動は「最小性」の効果を示すことを論じる。The ...
Taisuke NISHIGAUCHI, 西垣内 泰介
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source