Results 71 to 80 of about 8,766 (242)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

VC-minimality: Examples and Observations

open access: yes, 2020
. VC-minimality is a recent notion in model theory which generalizes strong minimality, o-minimality, weak o-minimality and c-minimality, but is strong enough to imply various other properties of interest such as NIP and dp-minimality.
Alice Medvedev   +3 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

1 Syntactic Codes and Grammar Refinement

open access: yes, 2008
. We call syntactic coding a technique which converts syntactic principles or constraints on representations into grammatical rules which can be implemented in any given rule grammar. In this paper we show that any principle or constraint on output trees
Marcus Kracht
core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

The relativized minimality approach to comprehension of German relative clauses in aphasia [PDF]

open access: yes
Personen mit Aphasie (PmA) verstehen Objektrelativsätze (ORS) häufig schlechter als Subjektrelativsätze (SRS). Im linguistisch basierten Ansatz der relativierten Minimalitätstheorie (RM; Rizzi, 1990, 2004) wird diese sog. Subjekt-Objekt-Asymmetrie dadurch erklärt, dass bei PmA aufgrund reduzierter Verarbeitungskapazitäten ein sog. Minimalitätseffekt in
openaire   +1 more source

Minimal positive realizations of transfer functions with nonnegative multiple poles [PDF]

open access: yes, 2005
This note concerns a particular case of the minimality problem in positive system theory. A standard result in linear system theory states that any nth-order rational transfer function of a discrete time-invariant linear single-input-single-output (SISO)
Matolcsi, Máté, Nagy, B.
core   +1 more source

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