Results 61 to 70 of about 24,582,015 (196)

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Relaxin reverses inflammatory and immune signals in aged hearts.

PLoS ONE, 2018
BACKGROUND:'Healthy' aging drives structural and functional changes in the heart including maladaptive electrical remodeling, fibrosis and inflammation, which lower the threshold for cardiovascular diseases such as heart failure (HF) and atrial ...
Brian Martin, Beth Ann Gabris-Weber, Rajiv Reddy, Guillermo Romero, Ansuman Chattopadhyay, Guy Salama   +5 more
doaj   +1 more source

Disturbed relaxin signaling pathway and testicular dysfunction in mouse offspring upon maternal exposure to simazine. [PDF]

PLoS ONE, 2012
Simazine is a triazine herbicide that is being widely applied worldwide and commonly detected in surface and groundwater. Despite its popular use in controlling weeds and algae, very limited information is available regarding its toxicity. In the present
Ho-Oak Park, Jeehyeon Bae
doaj   +1 more source

Oral contraceptive use and anterior cruciate ligament injury or reconstruction in women: A systematic review and meta‐analysis of very low‐certainty evidence

Journal of Experimental Orthopaedics, Volume 13, Issue 4, October 2026.
Abstract Purpose To determine whether oral contraceptive use is associated with anterior cruciate ligament injury or reconstruction in women and to examine whether associations vary according to age, contraceptive formulation, duration of use and outcome definition.
Eiki Nicholas Kobayashi, Natalia Zampa Silva, Laura Amaral Coelho de Azevedo, Maria Eugênia Cammarota de Abreu, Juliano Mangini Dias Malpaga, Diego Escudeiro de Oliveira, Pedro Baches Jorge   +6 more
wiley   +1 more source

Potential therapeutic use of relaxin in accelerating closure of cranial bone defects in mice

Physiological Reports, 2019
Bone fractures are associated with considerable morbidity and increased mortality. A major limitation to healing is lack of bone blood flow, which is impaired by physical disruption of intraskeletal and/or periosteal vasculature by the fracture.
Kirk P. Conrad, Ean G. Phillips, Jessica Jiron, Julie Bailes, Biswadeep Dhar, YanPeng Diao, Jose Ignacio Aguirre, Joshua F. Yarrow   +7 more
doaj   +1 more source

Clinical Efficacy and Mechanisms of ZiyuShuang, an Anti‐Skin Aging Formula Identified Through Network Medicine Framework Analysis

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Skin aging, a key aspect of physiological decline, markedly affects appearance, making strategies to delay it vital for quality of life. Materials and Methods We applied network medicine analysis to screen herbal medicines from the TCMSP database, yielding an anti‐skin aging formula, ZiYuShuang (ZYS).
Yingpeng Tong, Xiangmei Ni, Xinnan Jiang, Ru Zhang, Pengcheng Guo, Chunbo Feng, Jianxin Wang   +6 more
wiley   +1 more source

RELAXIN-3/RXFP3 systems and central stress- and anxiety-related circuits in mice

, 2022
RELAXIN-3/RXFP3 systems and central stress- and anxiety-related circuits in ...
E Timofeeva (13357596), A Yang (13621702), A L Gundlach (13357599), G Guevremont (13748434), Craig Smith (13065255), B Chua (13748431), C Zhang (2567170)   +6 more
core  

Relaxin in human thyroid neoplasias [PDF]

, 2010
Relaxin war für lange Zeit als Reproduktionshormon bekannt. In letzter Zeit wurden neue Ziele für Relaxin identifiziert. Meine Arbeit zeigt den Nachweis von Relaxin und RXFP1 Rezeptor in benignen und malignen Schilddrüsengeweben.
Bialek, Joanna
core   +1 more source

Relaxin-2 and Soluble Flt1 Levels in Peripartum Cardiomyopathy

JACC: Heart Failure, 2016
This study explored the association of vascular hormones with myocardial recovery and clinical outcomes in peripartum cardiomyopathy (PPCM).PPCM is an uncommon disorder with unknown etiology. Angiogenic imbalance may contribute to its pathophysiology.In 98 women with newly diagnosed PPCM enrolled in the Investigation in Pregnancy Associated ...
Julie, Damp, Michael M, Givertz, Marc, Semigran, Rami, Alharethi, Gregory, Ewald, G Michael, Felker, Biykem, Bozkurt, John, Boehmer, Jennifer, Haythe, Hal, Skopicki, Karen, Hanley-Yanez, Jessica, Pisarcik, Indrani, Halder, John, Gorcsan, Sarosh, Rana, Zoltan, Arany, James D, Fett, Dennis M, McNamara   +17 more
openaire   +2 more sources

Relaxin-2 Does Not Ameliorate Nephropathy in an Experimental Model of Type-1 Diabetes [PDF]

Kidney and Blood Pressure Research, 2015
<b><i>Background/Aims: </i></b>In diabetic nephropathy (DN), the current angiotensin-II-blocking pharmacotherapy is frequently failing. For diabetic cardiomyopathy (DC), there is no specific remedy available. Relaxin-2 (Rlx) - an anti-fibrotic, anti-inflammatory, and vasoprotecting peptide - is a candidate drug for both.
Dschietzig, Thomas Bernd, Krause-Relle, Katharina, Hennequin, Maud, von Websky, Karoline, Rahnenfuhrer, Jan, Ruppert, Jana, Groena, Hans Juergen, Armbruster, Franz Paul, Bathgate, Ross A. D., Aschenbach, Joerg R., Forssmann, Wolf-Georg, Hocher, Berthold (Prof.)   +11 more
openaire   +3 more sources