Results 91 to 100 of about 10,594 (253)

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

The Role of Extracellular Vesicles MicroRNAs in Sarcopenia: From Aging to Multi‐Morbidity

AGING MEDICINE, EarlyView.
Exosomes transporting miRNAs play a crucial bidirectional regulatory role in the process of sarcopenia, both in natural aging and under various pathological conditions. ABSTRACT Sarcopenia, defined as progressive loss of skeletal muscle mass and function, occurs during aging and has also been recognized for its detrimental effects in various disease ...
Bingyu Huang, Zhao Peng, Lin Kang
wiley   +1 more source

Myocardial ischaemia reperfusion injury: the challenge of translating ischaemic and anaesthetic protection from animal models to humans [PDF]

, 2016
Myocardial ischaemia reperfusion injury is the leading cause of death in patients with cardiovascular disease. Interventions such as ischaemic pre and postconditioning protect against myocardial ischaemia reperfusion injury. Certain anaesthesia drugs and
Irwin, MG, Li, H, Xia, Z
core   +1 more source

A Steerable and Expandable Magnetic Aspiration Catheter for Enhanced Aspiration Thrombectomy

Advanced Intelligent Systems, EarlyView.
This article presents a novel magnetic aspiration catheter (MAC) that can be both actively steered and undergo distal‐end expansion via externally applied magnetic fields. The MAC facilitates precise branch selection and enhances clot engagement by improving endovascular navigation and aspiration efficiency. Phantom experiments validate its feasibility
Hakjoon Lee, Xiao Dong, Dong‐in Kim, A. M. Masum Bulbul Chowdhury, Nader Latifi Gharamaleki, Jin‐young Kim, Sung Won Youn, Hongsoo Choi   +7 more
wiley   +1 more source

Remote Ischemic Conditioning in Cardiovascular Surgery.

Journal of cardiovascular pharmacology and therapeutics, 2017
The existing clinical studies on remote ischemic preconditioning in patients undergoing cardiovascular surgery are critically reviewed, with a focus on infarct size reduction and clinical outcome as end points. Confounders, notably the use of propofol anesthesia are identified.
openaire   +3 more sources

Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

Nature Communications, 2020
Necrotizing enterocolitis (NEC) is one of the most lethal gastrointestinal emergencies in neonates needing precision treatment. Here the authors show that remote ischemic conditioning is a non-invasive therapeutic method that enhances blood flow in the ...
Yuhki Koike, Bo Li, Niloofar Ganji, Haitao Zhu, Hiromu Miyake, Yong Chen, Carol Lee, Maarten Janssen Lok, Carlos Zozaya, Ethan Lau, Dorothy Lee, Sinobol Chusilp, Zhen Zhang, Masaya Yamoto, Richard Y. Wu, Mikihiro Inoue, Keiichi Uchida, Masato Kusunoki, Paul Delgado-Olguin, Luc Mertens, Alan Daneman, Simon Eaton, Philip M. Sherman, Agostino Pierro   +23 more
doaj   +1 more source

Prolonged low flow reduces reactive hyperemia and augments low flow mediated constriction in the brachial artery independent of the menstrual cycle [PDF]

, 2013
© 2013 Rakobowchuk et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
AE Devan, AM Malek, B Jiang, CM Pedersen, DHJ Thijssen, Emily R. Parsloe, Emma Harris, GP Fadini, J Pleiner, Karen M. Birch, KE Pyke, LE Spieker, M Rakobowchuk, Mark Rakobowchuk, MI Okorie, MW Broadhead, Nick Ashton, RA Harris, RK Kharbanda, Sarah E. Gibbins, SP Loukogeorgakis, SP Loukogeorgakis, SP Loukogeorgakis, T Gori, T Gori, T Gori, T Gori, TL Weissgerber   +27 more
core   +4 more sources

Short‐term remote ischemic conditioning may protect monkeys after ischemic stroke [PDF]

Annals of Clinical and Translational Neurology, 2019
AbstractObjectiveWe aimed to evaluate the safety and effectiveness of short‐term remote ischemic postconditioning (RIPC) in acute stroke monkey models.MethodsAcute stroke monkeys were allocated to four groups based on the number of limbs exposed to RIPC.
Guo, Linlin, Zhou, Da, Wu, Di, Ding, Jiayue, He, Xiaoduo, Shi, Jingfei, Duan, Yunxia, Yang, Tingting, Ding, Yuchuan, Ji, Xunming, Meng, Ran   +10 more
openaire   +2 more sources

Microrobotic Catheterization of the Ophthalmic Artery for Targeted Treatment of Retinoblastoma

Advanced Intelligent Systems, EarlyView.
A microrobotic platform is presented that allows teleoperated and autonomous navigation of flow‐driven magnetic microcatheters, MagFlow, into the ophthalmic artery for superselective intra‐arterial infusion of chemotherapy to treat retinoblastoma. Extensive benchtop validations with patient‐derived biomimetic phantoms under optical and fluoroscopic ...
Artur Banach, Mehdi Krichen, Julian Raub, Christina Stathopoulos, Bruno Bartolini, Mahmut Selman Sakar   +5 more
wiley   +1 more source

Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter [PDF]

, 2015
Remote ischemic postconditioning (RIPostC) is a promising therapeutic intervention whereby brief episodes of ischemia/reperfusion of one organ (limb) mitigate damage in another organ (brain) that has experienced severe hypoxia-ischemia.
Alonso-Alconada, Daniel, Bainbridge, Alan, Bennett, Kate, Broad, Kevin D, Ezzati, Mojgan, Fierens, Igor, Fleiss, Bobbi, Golay, Xavier, Gressens, Pierre, Hausenloy, Derek J, Hristova, Mariya, Jane Hassell, K, Kawano, Go, Lebon, Sophie, Oliver-Taylor, Aaron, Robertson, Nicola J, Rocha-Ferreira, Eridan, Rostami, Jamshid, Tachtsidis, Ilias, Yellon, Derek   +19 more
core   +2 more sources