Results 71 to 80 of about 10,594 (253)

New horizons for newborn brain protection: enhancing endogenous neuroprotection. [PDF]

open access: yes, 2015
Intrapartum-related events are the third leading cause of childhood mortality worldwide and result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult typically present with neonatal encephalopathy (NE).
Alonso-Alconada, D   +4 more
core   +2 more sources

Remote Ischemic Conditioning: A Clinical Trial’s Update

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2011
Coronary artery disease (CAD) is the leading cause of death and disability worldwide, and early and successful restoration of myocardial reperfusion following an ischemic event is the most effective strategy to reduce final infarct size and improve clinical outcome.
Luciano, Candilio   +2 more
openaire   +2 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Preclinical evidence of remote ischemic conditioning in ischemic stroke, a metanalysis update

open access: yesScientific Reports, 2021
Remote ischemic conditioning (RIC) is a promising therapeutic approach for ischemic stroke patients. It has been proven that RIC reduces infarct size and improves functional outcomes.
Coral Torres-Querol   +3 more
doaj   +1 more source

From Protecting the Heart to Improving Athletic Performance - the Benefits of Local and Remote Ischaemic Preconditioning [PDF]

open access: yes, 2015
Remote Ischemic Preconditioning (RIPC) is a non-invasive cardioprotective intervention that involves brief cycles of limb ischemia and reperfusion. This is typically delivered by inflating and deflating a blood pressure cuff on one or more limb(s) for ...
Cardinale, M   +5 more
core   +2 more sources

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

Remote Ischemic Conditioning for Patients With STEMI

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2017
ST-segment elevation myocardial infarction (STEMI) remains a leading cause of death and morbidity, despite declining incidence and improved short-term outcome in many countries. Although mortality declines in developed countries with easy and fast access to optimized treatment, development of heart failure often remains a challenge in survivors and ...
Schmidt, Michael Rahbek   +2 more
openaire   +3 more sources

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

Involvement of neuronal pathways in the protective effects of hindlimb perconditioning during renal ischemia [PDF]

open access: yes, 2017
Remote ischemic perconditioning (RPEC) is a therapeutic intervention that has been demonstrated to reduce renal ischemia/reperfusion (I/R) injury. However, the underlying renal protective mechanism remains unclear.
AHGHARI, PARISA   +6 more
core   +3 more sources

Elastomeric Micro‐Balloons for Remote Control of Cerebral Blood Flow and Real‐Time In vivo Imaging of Rodent Brain Response to Hypoperfusion

open access: yesAdvanced Materials, EarlyView.
This study reports the fabrication of MRI‐compatible elastomeric micro‐balloons via a multi‐step bubble casting process, where the monolithic elastomeric wall is selectively stiffened for reversible and controlled inflation and elasticity, depending on the target vessels for graded occlusion of cerebral arteries.
Jong Bin Kim   +10 more
wiley   +1 more source

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