Results 81 to 90 of about 10,594 (253)

Translational challenges of remote ischemic conditioning in ischemic stroke – a systematic review

Annals of Clinical and Translational Neurology, 2021
Remote ischemic conditioning (RIC) has well‐established cardioprotective effects in preclinical studies and promising results in preclinical stroke research.
Line Fuglsang Hansen, Nicholine S. K. Nielsen, Laura Cathrine Christoffersen, Christina Kruuse   +3 more
doaj   +1 more source

Intrinsic cardiac ganglia and acetylcholine are important in the mechanism of ischaemic preconditioning [PDF]

, 2017
This study aimed to investigate the role of the intrinsic cardiac nervous system in the mechanism of classical myocardial ischaemic preconditioning (IPC).
Burke, N, Davidson, SM, Pickard, JM, Yellon, DM   +3 more
core   +1 more source

3D‐Nanoprinted Fluidically Steerable Soft Robotic Microcatheters

Advanced Robotics Research, EarlyView.
This work introduces a ∼3‐French (1 mm‐in‐diameter) soft robotic microcatheter fabricated by means of two‐photon direct laser writing. The 3D‐printed microcatheter enables remote, on‐demand steering via microfluidic actuation for guidewire‐free navigation of vascular networks as well as microcatheter‐mediated delivery of fluidic payloads to target ...
Bailey M. Felix, Molly Carton, Olivia M. Young, Noah Barnes, Jordi T. Andreou, Sarah McHugh, Jack E. McCann, Claudia Davis, Victoria Reddig‐Leiman, Afsah Kamran, Dheeraj Gandhi, Miroslaw Janowski, Jeremy D. Brown, Mark Fuge, Axel Krieger, Clifford R. Weiss, Christopher R. Bailey, Ryan D. Sochol   +17 more
wiley   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Kaugisheemiline eelkohastamine – lihtne meetod elundikahjustuse vähendamiseks [PDF]

, 2015
Kaugisheemiline eelkohastamine (KIE) on meetod, mida kasutatakse sihtelundi isheemia-reperfusioonikahjustuse vähendamiseks. Meetod põhineb lühiajaliste isheemia- ja reperfusiooniepisoodide tekitamises, enamasti jäsemetel.
Eha, Jaan, Kals, Jaak, Kepler, Teele, Kuusik, Karl, Lepner, Urmas, Starkopf, Joel, Zilmer, Mihkel   +6 more
core   +2 more sources

Remote ischemic conditioning: the enigmatic transfer of protection [PDF]

Cardiovascular Research, 2017
This editorial refers to ‘Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning’ by Basalay et al. , doi: 10.1093/cvr/cvw216. Remote ischemic conditioning is the systemic response to brief non-lethal ischemia/reperfusion in various tissues or organs which provides protection to a number of target tissues or organs
openaire   +3 more sources

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Remote ischaemic conditioning reduces infarct size in animal in vivo models of ischaemia-reperfusion injury: a systematic review and meta-analysis [PDF]

, 2016
AIMS: The potential of remote ischaemic conditioning (RIC) to ameliorate myocardial ischaemia-reperfusion injury (IRI) remains controversial. We aimed to analyse the pre-clinical evidence base to ascertain the overall effect and variability of RIC in ...
Bromage, DI, Burke, N, Davidson, SM, Pickard, JM, Rossello, X, Yellon, DM, Ziff, OJ   +6 more
core   +1 more source

Remote Ischemic Conditioning in Elective PCI?

Journal of Cardiovascular Pharmacology and Therapeutics, 2017
This review examines the rationale for using remote ischemic conditioning (RIC) in elective percutaneous coronary intervention (PCI) to prevent procedure-related ischemia–reperfusion injury and justifies the importance of periprocedural biomarker elevation following elective PCI as a valid target for RIC. We review the evidence for the use of RIC as a
Joel P, Giblett, Stephen P, Hoole
openaire   +2 more sources