Results 41 to 50 of about 466,624 (293)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Working from Home, Telework, Equality and the Right to Privacy: A Study in Kazakhstan
Social Sciences, 2023 Remote work displays the flexibility of labor relations and expands the possibilities of conducting professional activities balanced with fulfilling personal needs.
Rassima Bayazitova +2 more
doaj +1 more source
Remote Working and Work Effectiveness: A Leader Perspective
International Journal of Environmental Research and Public Health, 2022 Currently, job duties are massively transferred from in-person to remote working. Existing knowledge on remote working is mainly based on employees’ assessment. However, the manager’s perspective is crucial in organizations that turned into remote work for the first time facing sudden circumstances, i.e., SARS-CoV-2 pandemic.
Grzegorz Kowalski, Katarzyna Ślebarska
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Distance Work Changes Strategy of HR Management
Вестник Российского экономического университета имени Г. В. Плеханова, 2020 The development of new means of telecommunications, such as IP-telephony, messengers, applications for videoconferencing, platforms for distance work with documents (for example, googleapps) and others have been promoting recently the change-over of ...
M. V. Milenin
doaj +1 more source
The future of work: financial implications of remote and hybrid work models [PDF]
The research subject pertains to urgent matters concerning the evolving character of work, obstacles in regulations, and financial approaches adopted by organisations.
Minthiva Pitchaya-Auckarakhun
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Behavioral Sciences, 2021 The ongoing epidemiological crisis has suddenly steered us towards a new futuristic work scenario in which most service sector employees work remotely, which could be a permanent reality for most service sector employees.
Paola Spagnoli +3 more
doaj +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
BALANCING ACT: SELF-LEADERSHIP AND THE HOME WORK ENVIRONMENT IN REMOTE WORK [PDF]
TramesThis study explores the relationship between self-leadership and the home-based work environment in the context of remote work. It examines how remote workers balance the duality of home as both a living and working space.
Anne Reino +3 more
doaj +1 more source