Ultrastructure of astrocytes using volume electron microscopy: A scoping review
Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini +7 more
wiley +1 more source
Endothelin-B Receptor Activation in Astrocytes Regulates the Rate of Oligodendrocyte Regeneration during Remyelination [PDF]
Timothy R. Hammond +5 more
openalex +1 more source
Fingolimod modulates microglial activation to augment markers of remyelination [PDF]
Samuel J. Jackson +2 more
openalex +1 more source
Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor [PDF]
Amin Sherafat +4 more
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Internalization of Exogenous Myelin by Oligodendroglia Promotes Lineage Progression
Oligodendroglia internalize extracellular myelin debris in vitro and in vivo. Internalized myelin modulates lipid metabolism and lipid droplet formation. Myelin‐derived signals promote oligodendroglial proliferation and lineage progression. ABSTRACT Oligodendrocytes, traditionally recognized for their role in central nervous system myelination, have ...
Carla Peiró‐Moreno +7 more
wiley +1 more source
Current advancements in promoting remyelination in multiple sclerosis [PDF]
David Kremer +3 more
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ABSTRACT Aim Indoles are tryptophan (Trp)‐derived metabolites that are produced by the gut microbiota and may influence the gut‐microbiota‐brain axis in multiple sclerosis (MS). Indole‐3‐lactate (ILA) is reduced in persons with MS and improves MS clinical scores in animal models via its anti‐inflammatory remyelinating properties.
Tiffany Wences Chirino +17 more
wiley +1 more source
OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease [PDF]
Wonjin Yun +17 more
openalex +1 more source
Causal Effect of Dietary Patterns on Cerebral Small Vessel Disease: A Mendelian Randomization Study
This Mendelian randomization (MR) study reveals causal links between dietary factors and cerebral small vessel disease (CSVD) neuroimaging markers. Genetically predicted higher polyunsaturated fatty acid (PUFA) levels reduce white matter hyperintensity volume, while monounsaturated fatty acid (MUFA) intake lowers lobar brain microbleeds (BMB) risk.
Yong Zeng +5 more
wiley +1 more source
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz +12 more
wiley +1 more source

