Astrocyte-Derived Endothelin-1 Inhibits Remyelination through Notch Activation [PDF]
, 2014 Timothy R. Hammond +6 more
openalex +1 more source
Quantitative magnetic resonance imaging reflects different levels of histologically determined myelin densities in multiple sclerosis, including remyelination in inactive multiple sclerosis lesions [PDF]
, 2023 Vanessa Wiggermann +6 more
openalex +1 more source
Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan +2 more
wiley +1 more source
Fibrin Inhibits Peripheral Nerve Remyelination by Regulating Schwann Cell Differentiation [PDF]
, 2002 Katerina Akassoglou +3 more
openalex +1 more source
Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.ABSTRACT Background and Aims Pathogenic variants in NEFL, the gene that encodes the light polypeptide subunit of neurofilaments, are an uncommon cause of autosomal recessive Charcot‐Marie‐Tooth (CMT) disease. In this study, we describe the clinical and electrophysiological features of two families with early‐onset CMT carrying nonsense variants in the ...
Marcus Vinícius Vieira da Silva Gomes +2 more
wiley +1 more source
Endothelin-B Receptor Activation in Astrocytes Regulates the Rate of Oligodendrocyte Regeneration during Remyelination [PDF]
, 2015 Timothy R. Hammond +5 more
openalex +1 more source
Restless Legs Syndrome in Patients With PMP22‐Related Neuropathies
Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.ABSTRACT Background and Aims Restless legs syndrome (RLS) is frequently reported in peripheral neuropathies, but its prevalence and clinical correlates in Charcot–Marie–Tooth disease type 1A (CMT1A) and hereditary neuropathy with liability to pressure palsies (HNPP) remain poorly defined.
Bogdan Bjelica +7 more
wiley +1 more source
Remyelinating Drugs at a Crossroad: How to Improve Clinical Efficacy and Drug Screenings
CellsAxons wrapped around the myelin sheath enable fast transmission of neuronal signals in the Central Nervous System (CNS). Unfortunately, myelin can be damaged by injury, viral infection, and inflammatory and neurodegenerative diseases.
Aland Ibrahim Ahmed Al Jaf +3 more
doaj +1 more source
Current advancements in promoting remyelination in multiple sclerosis [PDF]
, 2018 David Kremer +3 more
openalex +1 more source
Phenol Neurolysis in Pain and Palliative Medicine
Pain Practice, Volume 26, Issue 5, June 2026.ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers +6 more
wiley +1 more source