Results 81 to 90 of about 26,726 (251)
Animal Models and Experimental Medicine, EarlyView.Animal models enable mechanistic testing of how ischemic injury disrupts neurovascular trafficking and drives cognitive vulnerability after stroke. Complementary models capture distinct vascular, cellular, white matter, and cognitive features of PSCI.
Pratchaya Kaewkaen
wiley +1 more source
, 2018 Introduction: Experimental autoimmune encephalomyelitis (EAE) and lysophosphatidylcholine (LPC)-induced demyelination are common rodent models of multiple sclerosis (MS).
Lamport, Anna Claire
core
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Food Chemistry International, EarlyView.The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi +2 more
wiley +1 more source
Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α
Cell Reports, 2018 Summary: Remyelination is a multistep regenerative process that results in the reformation of myelin sheaths around demyelinated axons and is a critical therapeutic target.
Samuel K. Jensen +5 more
doaj +1 more source
Myelination and Remyelination in Peripheral Nerve Injury: Mechanisms, Regulation, and Therapeutic Perspectives [PDF]
MedComm (2020)Peripheral nerve injury triggers axonal degeneration, myelin breakdown, and Schwann cell reprogramming. Remyelination requires reactivation of the SOX10–OCT6–KROX20/EGR2 transcriptional hierarchy, axonal NRG1–ErbB2/3 signaling, metabolic support, and coordinated immune regulation.
Huang L +13 more
europepmc +2 more sources
Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration
FlexTech, EarlyView.Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley +1 more source
Remyelination In Multiple Sclerosis
, 2007 Remyelination is the phenomenon by which new myelin sheaths are generated around axons in the adult central nervous system (CNS). This follows the pathological loss of myelin in diseases like multiple sclerosis (MS). Remyelination can restore conduction properties to axons (thereby restoring neurological function) and is increasingly believed to exert ...
openaire +2 more sources
Toward a transgenic mouse model of remyelination
, 1997 The molecular mechanisms necessary for remyelination by oligodendrocytes remain unexplored. We previously characterized a myelin basic protein promoter-lacZ (MBP-lacZ) transgene whose expression is regulated uniquely during development, and also in ...
S. Ferraresi +6 more
core +1 more source
Hydrogel‐Based Bioelectronics: From Therapy and Sensing to Neuromorphic Computation
FlexTech, EarlyView.This review establishes a material–conduction–property–application framework connecting hydrogel chemistry and charge transport with therapy, sensing, closed‐loop feedback, and neuromorphic computation. ABSTRACT Bioelectronics establish bidirectional communication between living systems and electronic devices, providing an enabling platform for ...
Jianlong Hong +7 more
wiley +1 more source