Results 61 to 70 of about 22,271 (244)
Movement Disorders, EarlyView.Abstract Background Ultrasound‐based neuromodulation, capable of reaching deep brain areas with high precision, represents cutting‐edge technology in non‐invasive brain stimulation and is investigated as a novel treatment for neurological and psychiatric disorders, including Parkinson's disease (PD).
Eva Matt +14 more
wiley +1 more source
Macrophages Regulate Schwann Cell Maturation after Nerve Injury
Cell Reports, 2018 Summary: Pro-regenerative macrophages are well known for their role in promoting tissue repair; however, their specific roles in promoting regeneration of the injured nerve are not well defined.
Jo Anne Stratton +8 more
doaj +1 more source
Remyelination of the injured spinal cord [PDF]
, 2007 Contusive spinal cord injury (SCI) can result in necrosis of the spinal cord, but often long white matter tracts outside of the central necrotic core are demyelinated. One experimental strategy to improve functional outcome following SCI is to transplant myelin-forming cells to remyelinate these axons and improve conduction.
Masanori, Sasaki +4 more
openaire +2 more sources
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To investigate the utility of a recently demonstrated diffusion MRI derived axon diameter surrogate measure (∆D⟂) under pathologic conditions induced by a spinal cord injury model. Methods Contusion injuries were performed on the thoracic–lumbar spinal cord of adult male rats.
Hannah E. Alderson +4 more
wiley +1 more source
Ischemia-Induced Cognitive Impairment Is Improved via Remyelination and Restoration of Synaptic Density in the Hippocampus after Treatment with COG-Up® in a Gerbil Model of Ischemic Stroke [PDF]
, 2021 Tae-Kyeong Lee +9 more
openalex +1 more source
Neuroprotection, EarlyView.The critical transition from amyloid pathology to irreversible neuronal loss in Alzheimer's disease hinges on the microglial response. This review aims to systematize the patterns of how microglia react within the glial context. Abstract Microglia mount coordinated, stage‐dependent compensatory programs in response to early amyloid β (Aβ) accumulation ...
Songtao Lei +3 more
wiley +1 more source
Myeloid cell-associated aromatic amino acid metabolism facilitates CNS myelin regeneration
npj Regenerative MedicineRegulation of myeloid cell activity is critical for successful myelin regeneration (remyelination) in demyelinating diseases, such as multiple sclerosis (MS).
Jingwen Hu +14 more
doaj +1 more source
Brain Pathology, EarlyView.Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios +18 more
wiley +1 more source
Myelin Damage and Repair in Pathologic CNS: Challenges and Prospects
Frontiers in Molecular Neuroscience, 2015 Injury to the central nervous system (CNS) results in oligodendrocyte cell death and progressive demyelination. Demyelinated axons undergo considerable physiological changes and molecular reorganizations that collectively result in axonal dysfunction ...
Arsalan eAlizadeh +2 more
doaj +1 more source
Equine Veterinary Education, EarlyView.Summary A 2‐year‐old Arabian filly presented with acute onset grade 4/5 (AAEP) right forelimb lameness and hindlimb ataxia following a collision with another horse and subsequent fall. The right forelimb lameness was associated with marked scapulohumeral joint instability.
O. E. Newman, B. Dunkel, M. Perrier
wiley +1 more source