Involvement of Apolipoprotein E in Multiple Sclerosis: Absence of Remyelination Associated with Possession of theAPOEε2 Allele [PDF]
Christopher Carlin+4 more
openalex +1 more source
Astrocytes display heterogeneity in various neurological disorders and behavioral neuropsychiatric disorders. Astrocytes influence the progression of neurological diseases through neuroinflammation, oxidative stress, metabolic abnormalities, intercellular interactions, and a spectrum of other pathophysiological processes.
Shijie Mao+12 more
wiley +1 more source
Background Multiple sclerosis (MS) is a chronic demyelinating disease characterized by autoimmune attacks on myelin sheaths. Its deleterious effects may be reversed by remyelination, a process that restores the integrity of myelin sheaths and ...
Ander Egimendia+6 more
doaj +1 more source
The Neurotoxicant, Cuprizone, as a Model to Study Demyelination and Remyelination in the Central Nervous System [PDF]
Glenn K. Matsushima, Pierre Morell
openalex +1 more source
Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin‐induced demyelination [PDF]
Mark Kotter+4 more
openalex +1 more source
Repairing Myelin After Irradiated Pediatric Brain Tumor: A Magnetization Transfer Imaging Analysis
ABSTRACT Background While exercise training and metformin treatment have demonstrated preliminary cognitive improvements in pediatric brain tumor (PBT) survivors, the neuronal mechanisms underlying their cognitive improvements are unclear. Diffusion‐weighted metrics (e.g., fractional anisotropy [FA]) are commonly used to evaluate remyelination, but ...
Éloïse Baudou+7 more
wiley +1 more source
Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis [PDF]
Paul D. Murray+3 more
openalex +1 more source
A quantitative morphometric analysis of rat spinal cord remyelination following transplantation of allogenic Schwann cells [PDF]
Karen L. Lankford+3 more
openalex +1 more source
We have sought to determine the role that cholesterol metabolism plays in disability worsening and its correlation with progressive MS by analysing patient CSF and post‐mortem tissues using cutting edge mass spectrometry approaches. Key sterol metabolites measured in the CSF link with important disability milestones at the very early stages of MS ...
Lauren Griffiths+13 more
wiley +1 more source
The landscape of targets and lead molecules for remyelination
A. Caprariello, Drew J. Adams
semanticscholar +1 more source