Results 141 to 150 of about 26,726 (251)

Agrin‐Enriched Neonatal Spinal Cord‐Derived Extracellular Vesicles Bypass Age Barriers to Organize Spinal Cord Repair

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Spinal cord injury (SCI) poses a formidable challenge in regenerative medicine, with current therapeutic strategies proving largely unsuccessful in achieving functional repair. Notably, paediatric patients and neonatal mice exhibit spontaneous and efficient regeneration after SCI, while the mechanisms remain elusive.
Yongfeng Zhang, Qi Liu, Beibei Yu, Borui Xue, Shijie Yang, Teng Ma, Lingli Guo, Haining Wu, Xue Gao, Shengyou Li, Yujie Yang, Yiming Hao, Ziqing Zhu, Meijia Su, Hongyu Li, Shuanshuan Fan, Jiaqi Wang, Huangtao Chen, Longhui Fu, Anhui Qin, Zhenguo Wang, Shihao Nie, Mingze Qin, Xinxin Bai, Guang Kong, Rui Zhao, Dong Lei, Yue Yu, Junxiong Ma, Shouping Gong, Bing Xia, Jinghui Huang   +31 more
wiley   +1 more source

Effects of sphingosine-1-phosphate receptor modulators on remyelination in multiple sclerosis: evidence from <i>in vitro</i> experiments, animal models and human studies. [PDF]

Front Immunol
Ricigliano VAG.
europepmc   +1 more source

Multiparametric Quantitative MRI of Peripheral Nerves to Differentiate Demyelinating From Axonal Polyneuropathies

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1077-1088, October 2026.
ABSTRACT Background Differentiating demyelinating from axonal polyneuropathies helps for accurate diagnosis and treatment. However, the current clinical tools lack sensitivity to confirm demyelination in peripheral nerves, particularly for proximal nerves.
Jesus E. Fajardo, Vivian B. Truong, Yang Xuan, Sara E. Benitez, Mary L. Vo, Bo Hu, Richard D. Dortch, Jun Li, Yongsheng Chen   +8 more
wiley   +1 more source

Microglial handling of myelin debris and remyelination after ischaemic stroke: recognition, intracellular processing, lipid fate, and oligodendroglial repair. [PDF]

Front Cell Neurosci
Song M, Bu N, Wei L, Chen J.
europepmc   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo, Francesco Marocco, Clemens Zwergel, Marco Tripodi, Cecilia Battistelli   +4 more
wiley   +1 more source

Crosstalk Between Oligodendrocyte Lineage Cells and CNS-Resident and Peripheral Immune Cells Governs Demyelination and Remyelination in Multiple Sclerosis. [PDF]

Glia
Park J, Cheon SY, Guo F.
europepmc   +1 more source

Remyelination in the Central Nervous System

The inability of the mammalian central nervous system (CNS) to undergo spontaneous regeneration has long been regarded as a central tenet of neurobiology.
Franklin, Robin J.M., Bodini, Benedetta, Goldman, Steven A.   +2 more
core   +1 more source

The Neurovascular Niche: A Gathering Venue for Neuroinflammation and Remyelination in Multiple Sclerosis. [PDF]

Acta Physiol (Oxf)
Kazanis I, Silva ME, de la Fuente AG, de Castro F, Rivera FJ.   +4 more
europepmc   +1 more source

Selective inhibition of TLR2 stimulates the maturation of oligodendroglial progenitor cells to oligodendrocytes. [PDF]

NeuroImmune Pharm Ther
Chakrabarti S, Jana M, Gorai S, Pahan K.
europepmc   +1 more source

Laminin Expression and Function in the Central Nervous System

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT Laminin, an extracellular matrix protein with multiple isoforms, is a key component of the basal lamina. In the central nervous system (CNS), different cells synthesize distinct laminin isoforms, which exert a diverse range of functions, including blood‐brain barrier maintenance/repair, cell survival/migration/differentiation, myelination ...
Lingling Xu, Sarah Yuan, Yao Yao
wiley   +1 more source