Results 151 to 160 of about 26,726 (251)

Molecular Mediators Associated With Myelination, Demyelination, and Remyelination in the Peripheral Nervous System. [PDF]

J Peripher Nerv Syst
Hagen KM, Ousman SS.
europepmc   +1 more source

From Regenerative to Degenerative Niche: Multicellular Crosstalk and Population Dynamics in Skeletal Muscle Aging

Aging Cell, Volume 25, Issue 10, October 2026.
Aging transforms the skeletal muscle microenvironment from a balanced, regenerative niche into a maladaptive, degenerative state. This review highlights how disrupted multicellular crosstalk drives chronic inflammation, fibrosis, and neuromuscular dysfunction, ultimately compromising tissue repair and fueling sarcopenia.
Seongwan Kim, Min Ju Kim, Yong Ryoul Yang   +2 more
wiley   +1 more source

Stress-induced tunneling nanotube communication in CNS glial cells: implications for inflammatory demyelination and repair failure. [PDF]

Front Cell Neurosci
Liu Y, Li M, Liu W, Guo J, Yin J.
europepmc   +1 more source

The Role of Peripheral Myelin Protein 2 in Remyelination

, 2018
The protein component of the myelin layer isessential for all aspects of peripheral nerves, and its deficiencycan lead to structural and functional impairment.The presence of peripheral myelin protein 2 (P2, PMP2,FABP8, M-FABP) in Schwann cells has been ...
Stettner, Mark...[et al.]
core  

Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many Functions

European Journal of Neuroscience, Volume 64, Issue 7, October 2026.
Oligodendrocyte progenitor cells (OPCs) are increasingly recognised as multifunctional CNS cells rather than mere precursors of myelinating oligodendrocytes. Alongside myelination and remyelination, they contribute to myelin and circuit plasticity, circuit regulation, vascular and blood–brain barrier regulation and neuroimmune modulation.
Alerie G. de la Fuente
wiley   +1 more source

A novel small molecule remyelination therapy for multiple sclerosis. [PDF]

NPJ Drug Discov
Yang Y, Bai B, Knutsen LJS, Hamlyn RJ, Cui QL, Antel J, Macklin W, Medicetty S, Trapp BD.   +8 more
europepmc   +1 more source

Treadmill Exercise Can Modulate the Inflammatory Microenvironment and Promote Regeneration After Compressive Spinal Cord Injury in Female Mice

Journal of Cellular and Molecular Medicine, Volume 30, Issue 20, October 2026.
ABSTRACT Traumatic spinal cord injury (SCI) leads to severe sensorimotor impairments and reduced quality of life. Physical rehabilitation has emerged as a key therapeutic strategy to improve function and mitigate complications such as muscle atrophy and joint contractures, partly through modulation of the inflammatory microenvironment.
Anne Caroline Rodrigues dos Santos Cavalcante, Renata Pereira Laurindo, Luiza dos Santos Heringer, Anna Lecticia Martinez Martinez Toledo, Gabriela Sena Souza, Gabriel Fidalgo Queiroz da Silva, Ana Carolina Campos dos Santos, Morgana Teixeira Lima Castelo Branco, Ana Maria Blanco Martinez, Suelen Adriani Marques   +9 more
wiley   +1 more source

SUN11602 Accelerates Early Peripheral Nerve Regeneration in an Experimental Median Nerve Transection Model

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Peripheral nerve injury (PNI) is one of the common life‐altering disabilities resulting in various degrees of impairment in movement and sensation alongside apraxia and long‐lasting pain. The gold standard for restoring the transected nerves is bridging the distal and proximal ends of disrupted autologous nerve using neurosurgical sutures ...
Giovanna Casili, Igor Papalia, Alessio Ardizzone, Rossella Basilotta, Alfio Luca Costa, Paolo Titolo, Emanuela Esposito, Michele Rosario Colonna, Mariarosaria Galeano   +8 more
wiley   +1 more source

Multifaceted response of microglia in the cuprizone model of demyelination. [PDF]

PLoS One
Shanahan A, Eichfeld G, Todd L, Niraula A.   +3 more
europepmc   +1 more source

PINK1 and PARKIN Deficiency Increases Neuronal Vulnerability to Autoimmune Neuroinflammation Through Mitochondrial Fragmentation in Aged Mice

Journal of Neurochemistry, Volume 170, Issue 10, October 2026.
PINK1 and Parkin help protect the nervous system during inflammation. When either protein is missing, autoimmune inflammation becomes more severe and neurons show greater mitochondrial abnormalities and damage, particularly with aging. These findings reveal how defective mitochondrial maintenance can make the brain more vulnerable to inflammatory ...
Davide Cossu, Sachiko Noda, Shigeto Sato, Kazumasa Yokoyama, Yuji Tomizawa, Ruochen Wang, Sarah Vascellari, Leonardo Antonio Sechi, Taku Hatano, Nobutaka Hattori   +9 more
wiley   +1 more source