Results 201 to 210 of about 41,992 (300)
Astrocyte in Neurological Disease: Pathogenesis and Therapy
MedComm, Volume 6, Issue 8, August 2025.This review provides comprehensive overview of astrocytes in neurological disorders. Astrocytes contribute to neurological disorders via A1/A2 polarization, inducing neuroinflammation, synaptic, and BBB dysfunction. Metabolic disturbances in glucose, lipid, and amino acid pathways leading to oxidative stress and mitochondrial damage.
Meihui Huang +4 more
wiley +1 more source
Early events in node of Ranvier formation during myelination and remyelination in the PNS [PDF]
, 2006 Dorothy P. Schafer +3 more
openalex +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
MedComm, Volume 6, Issue 8, August 2025.Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng +10 more
wiley +1 more source
The pro-remyelination properties of microglia in the central nervous system
Nature Reviews Neurology, 2019 Amy F Lloyd, V. Miron
semanticscholar +1 more source
GSK3β regulates oligodendrogenesis in the dorsal microdomain of the subventricular zone via Wnt-β-catenin signaling [PDF]
, 2014 Azim, Kasum +3 more
core +1 more source
Mitochondrial Quality Control in Health and Disease
MedComm, Volume 6, Issue 8, August 2025.Mitochondrial quality control (MQC) maintains cellular homeostasis by coordinating various processes such as fission, fusion, mitophagy, and mitochondria‐regulated cell death. Dysregulation of these mechanisms plays a key role in the development of many human diseases.
Lin Ye, Xinzhi Fu, Qi Li
wiley +1 more source
Addiction Biology, Volume 30, Issue 8, August 2025.Treadmill exercise improved METH‐induced learning and memory impairment in mice.Transcriptome analysis revealed that exercise modulated key pathways including PI3K‐Akt, mTOR, and Wnt signaling. NFKBIA, CXCL12, and Vav3 were identified as potential mediators of the beneficial effects.
Qiuyue Huang +6 more
wiley +1 more source
Clinical and Experimental Neuroimmunology, Volume 16, Issue 3, Page 208-213, August 2025.ABSTRACT Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease. While typically diagnosed in young adults, late‐onset MS (LOMS, onset > 50 years) is becoming increasingly recognized, presenting with distinct features such as higher rates of progressive onset and motor symptoms.
Takuya Matsushita
wiley +1 more source
Cell Proliferation, Volume 58, Issue 8, August 2025.Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin +4 more
wiley +1 more source