Results 211 to 220 of about 22,271 (244)

Signaling for Remyelination

Science Signaling, 2013
Inhibiting SIRT1 may improve demyelinating neuropathies by inducing the expansion of myelin-producing oligodendrocytes.
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Remyelination: Cellular and gene therapy

Seminars in Pediatric Neurology, 1998
Dysfunctional myelination or oligodendroglial abnormalities play a prominent role in a vast array of pediatric neurological diseases of genetic, inflammatory, immunological, traumatic, ischemic, developmental, metabolic, and infectious causes. Recent advances in glial cell biology have suggested that effective remyelination strategies may, indeed, be ...
L L, Billinghurst, R M, Taylor, E Y, Snyder   +2 more
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Transcriptional control of myelination and remyelination

Glia, 2019
AbstractMyelination is an evolutionary recent differentiation program that has been independently acquired in vertebrates by Schwann cells in the peripheral nervous system and oligodendrocytes in the central nervous system. Therefore, it is not surprising that regulating transcription factors differ substantially between both cell types.
Elisabeth Sock, Michael Wegner
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Human oligodendrocytes in remyelination research

Glia, 2014
Studies on myelination and oligodendrocyte development are inevitably linked with demyelinating conditions such as multiple sclerosis (MS), leukodystrophies or spinal cord injury (SCI). Chronic loss of myelin, subsequently leading to neurodegeneration, is the ultimate cause of severe and permanent disability. Thus, fast restoration
Marcin, Czepiel, Erik, Boddeke, Sjef, Copray   +2 more
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Evolving Concepts and Issues in Remyelination

Developmental Neuroscience, 1989
The ability of the central nervous system to undergo remyelination is now well established in both clinical and experimental situations. The focus of investigation has shifted from simple morphologic documentation to a detailed examination of the basic biologic processes controlling or limiting remyelination.
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Remyelination: a brief history

The Lancet Neurology, 2020
Catherine, Lubetzki, Bernard, Zalc
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Remyelination in Human CNS Lesions

1980
Publisher Summary Medical prognosis with regard to human CNS lesions has been poor— the general view being that most of these lesions show no tendency to functional recovery. Studies on Wallerian and retrograde degeneration, in particular, gave the impression that repair in the CNS is a rare phenomenon as the axon as well as the myelin sheath ...
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Revisiting remyelination: Towards a consensus on the regeneration of CNS myelin

Seminars in Cell and Developmental Biology, 2021
Robin J M Franklin, Jonas Frisen, David A Lyons   +2 more
exaly  

Transnodal remyelination

The Journal of Pathology, 1970
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Imaging of Remyelination and Neuronal Health

2008
Remyelination of axons that have been demyelinated due to multiple sclerosis (MS) may be a critical step in restoring the damaged axons and reversing the disease process. While it is possible to establish the presence of remyelination with microscopy of tissue samples, it is important to have noninvasive or minimally invasive methods to measure ...
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