Results 21 to 30 of about 624,431 (182)

Renal hypouricemia complicated with kidney stone: a case report [PDF]

Frontiers in Medicine
Renal hypouricemia (RHUC) is a rare autosomal recessive disorder characterized by impaired renal tubular uric acid reabsorption and abnormally high uric acid clearance, which may be manifested by reduced serum uric acid (SUA) levels and elevated ...
Yuhao Yang, Xingyu Mu, Zengxiang Wu, Zhenmei An, Shuangqing Li   +4 more
doaj   +2 more sources

Identification of a Hypouricemia Patient with SLC2A9 R380W, A Pathogenic Mutation for Renal Hypouricemia Type 2 [PDF]

Nucleosides, Nucleotides and Nucleic Acids, 2014
Hypouricemia is characterized by low serum uric acid (SUA) levels (≤3.0 mg/dL) with complications such as urolithiasis and exercise-induced acute renal failure. We have previously reported that urate transporter 1 (URAT1/SLC22A12) and glucose transporter 9 (GLUT9/SLC2A9) are causative genes for renal hypouricemia type 1 (RHUC1) and renal hypouricemia ...
Toshinori, Chiba, Hirotaka, Matsuo, Shushi, Nagamori, Akiyoshi, Nakayama, Yusuke, Kawamura, Seiko, Shimizu, Masayuki, Sakiyama, Makoto, Hosoyamada, Sayo, Kawai, Rieko, Okada, Nobuyuki, Hamajima, Yoshikatsu, Kanai, Nariyoshi, Shinomiya   +12 more
openaire   +4 more sources

Renal effects of uric acid: hyperuricemia and hypouricemia [PDF]

The Korean Journal of Internal Medicine, 2020
The prevalence of chronic kidney disease (CKD) is increasing worldwide. Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function.
Jung Hwan Park, Yong-Il Jo, Jong-Ho Lee
doaj   +4 more sources

Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion [PDF]

BMC Medical Genetics, 2020
Background Renal hypouricemia (RHUC) is a hereditary disorder where mutations in SLC22A12 gene and SLC2A9 gene cause RHUC type 1 (RHUC1) and RHUC type 2 (RHUC2), respectively.
Motohiro Sekiya, Takaaki Matsuda, Yuki Yamamoto, Yasuhisa Furuta, Mariko Ohyama, Yuki Murayama, Yoko Sugano, Yoshinori Ohsaki, Hitoshi Iwasaki, Naoya Yahagi, Shigeru Yatoh, Hiroaki Suzuki, Hitoshi Shimano   +12 more
doaj   +2 more sources

Unmasking the silent culprit: recurrent exercise-induced acute kidney injury in a Chinese adolescent with renal hypouricemia [PDF]

Renal Failure
Primary renal hypouricemia (RHUC) is a rare autosomal recessive disorder with a mean duration of end-stage acute kidney injury (EIAKI) of 14 days. The pathogenesis of EIAKI in patients with RHUC remains unclear.
Yuan Gao, Lu Xu, Mingming Wei, Xiaohan Qu, Tongtong Pan, Xinjian Li   +5 more
doaj   +2 more sources

A Case of Acute Kidney Injury in a Patient with Renal Hypouricemia without Intense Exercise [PDF]

Case Reports in Nephrology and Dialysis, 2020
Exercise-induced acute kidney injury (EIAKI) frequently develops in patients with renal hypouricemia (RHUC). However, several cases of RHUC with acute kidney injury (AKI) but without intense exercise have been reported.
Daiki Aomura, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Yuji Kamijo   +4 more
doaj   +2 more sources

Uric Acid Extremes and Lipid Dysregulation: Evidence from a Large Population-Based Study [PDF]

Metabolites
Background: Uric acid (UA) exhibits a dual role, with anti-oxidant or pro-oxidant effects determined by its concentration. However, its association with lipid metabolism across different uric acid states remains unclear.
Yazeed Alshuweishi, Ahmed M. Basudan, Zeina S. Alkudmani, Mohammad A. Alfhili   +3 more
doaj   +2 more sources

Clinical Features Suggesting Renal Hypouricemia as the Cause of Acute Kidney Injury: A Case Report and Review of the Literature [PDF]

Journal of Nephrology, 2023
Fiammetta Ravaglia, Viviana Palazzo, Luigi Cirillo   +2 more
exaly   +2 more sources

Renal hypouricemia as the cause of exercise-induced acute kidney injury [PDF]

Kidney Research and Clinical Practice, 2023
Haeun Lee, Donghyuk Kang, Hanbi Lee, Jisook Yim, Myungshin Kim, Cheol Whee Park   +5 more
doaj   +2 more sources

A Case of Tachycardia-Induced Acute Kidney Injury by Renal Hypouricemia [PDF]

Journal of Cardiology Cases
Yusuke Kawamura, Atsuhito Takeda, Gaku Izumi   +2 more
exaly   +2 more sources