Results 31 to 40 of about 624,431 (182)
The in-silico evaluation of important GLUT9 residue for uric acid transport based on renal hypouricemia type 2. [PDF]
Chem Biol Interact, 2023 Uric acid is the end product of purine metabolism. Uric acid transporters in the renal proximal tubule plays a key role in uric acid transport. Functional abnormalities in these transporters could lead to high or low levels of uric acid in the blood ...
Cachau R, Shahsavari S, Cho SK.
europepmc +2 more sources
A novel mutation in a patient with familial renal hypouricemia type 2
Nefrología (English Edition), 2022 Introduction: Hypouricemia may be caused by disorders leading to decreased UA production, oxidation of UA to allantoin by drugs or increased renal tubular loss of filtered UA, renal hypouricemia (RHUC).
Kubra Kaynar +4 more
doaj +3 more sources
Altered Serum Uric Acid Levels in Kidney Disorders
Life, 2022 Serum uric acid levels are altered by kidney disorders because the kidneys play a dominant role in uric acid excretion. Here, major kidney disorders which accompany hyperuricemia or hypouricemia, including their pathophysiology, are discussed.
Gheun-Ho Kim, Jae-Bum Jun
doaj +1 more source
Hematuria in Patients with Renal Hypouricemia.
Internal Medicine, 1998 The characteristics of urate metabolism in renal hypouricemic patients with hematuria were studied to clarify the risk factors for hematuria in patients with renal hypouricemia. In 16 Japanese patients with isolated renal hypouricemia, urate metabolism was measured using the urate clearance study and the subtype of renal hypouricemia [defective ...
HISATOME, Ichiro +15 more
openaire +3 more sources
Impact of Hyper- and Hypo-Uricemia on Kidney Function
Biomedicines, 2023 Uric acid (UA) forms monosodium urate (MSU) crystals to exert proinflammatory actions, thus causing gout arthritis, urolithiasis, kidney disease, and cardiovascular disease. UA is also one of the most potent antioxidants that suppresses oxidative stress.
Junichiro Miake +7 more
doaj +1 more source
A case of idiopathic renal hypouricemia.
Nihon Naika Gakkai Zasshi, 1994 分泌前再吸収障害型と診断された特発性腎性低尿酸血症(血清尿酸値0.7mg/dl)の1例を報告する.今回,従来の報告では検討されたことのないパラアミノ馬尿酸(PAH)の尿細管分泌極量(TmPAH)を測定したところ, 85.1mg/minと正常値を示し,尿酸の転送機構のみが障害されていることが証明された.
H, Matsuda +6 more
openaire +3 more sources
Renal Replacement Therapy, 2020 Background/aims Familial juvenile hereditary nephropathy (FJHN) is characterized by hyperuricemia due to severely impaired urinary excretion of urate. Hereditary renal hypouricemia is an inborn error of membrane transport.
Fateme Shamekhi Amiri, Zohreh Rostami
doaj +1 more source
Nefrología (English Edition), 2019 Hereditary renal hypouricemia is a rare autosomal recessive genetic disorder that involves an isolated defect in uric acid reabsorption at the renal tubules.
Amelia Peris Vidal +7 more
doaj +1 more source
Nefrología, 2019 Resumen: La hipouricemia renal hereditaria es un trastorno genético, poco frecuente, causado por un defecto aislado en la reabsorción del ácido úrico a nivel del túbulo renal.
Amelia Peris Vidal +7 more
doaj +1 more source
, 2015 [Abstract] Patients with the disease entity termed acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise (ALPE) manifests non-oliguric renal failure, usually accompanied by few urinary abnormalities such as ...
ニシ, ヒトミ +13 more
core +1 more source