Results 141 to 150 of about 17,448,568 (253)

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura   +6 more
wiley   +1 more source

High urine osmolality and elevated urine sodium predict early nonresponse to fluid restriction in patients with the syndrome of inappropriate antidiuresis

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Introduction Fluid restriction is the current first‐line therapy for hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD), yet up to 50% of patients do not achieve an adequate plasma sodium correction. Reported predictors of nonresponse include urine osmolality >500 mOsm/kg, the Furst ratio >1 [(UNa + UK)/(PNa)], urine ...
Michelle Patricia Müller   +5 more
wiley   +1 more source

The Role of the Renin-Angiotensin-Aldosterone System in Hypertensive Emergencies. [PDF]

open access: yesBiomedicines
Minari TP   +10 more
europepmc   +1 more source

Effect of Sotagliflozin on Kidney Function and Cardio‐Kidney‐Metabolic Parameters Across Baseline eGFR Subgroups in Patients With Type 2 Diabetes and Stage 4 CKD

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Vikas S. Sridhar   +4 more
wiley   +1 more source

Targeting Overweight and Obesity Phenotypes for Secondary Prevention of Cardiovascular Disease: A Call to Action for the Middle East and Beyond

open access: yesObesity Reviews, EarlyView.
ABSTRACT Although there are conflicting clinical data on the efficacy of weight reduction in reducing secondary events in patients with comorbid overweight and obesity (OAO) and cardiovascular disease (CVD), there is excellent epidemiological and biological evidence of a cause–effect relationship between OAO, CVD, and other systemic complications ...
Wael Almahmeed   +19 more
wiley   +1 more source

Myeloid cell renin-angiotensin-aldosterone system in hypertension and inflammation. [PDF]

open access: yesCurr Opin Physiol
Albritton CF   +4 more
europepmc   +1 more source

Transcriptome Analysis Reveals Distinct Molecular Signatures Between Erosive and Non‐Erosive Oral Lichen Planus

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen   +5 more
wiley   +1 more source

Influence of menstrual cycle phase on inflammatory and vascular responses to acute passive heating in healthy young women

open access: yesExperimental Physiology, EarlyView.
Abstract The aim of this study was to determine whether inflammatory and vascular responses to passive heating differ between the early follicular phase (EFP) and the mid‐luteal phase (MLP) of the menstrual cycle. Ten healthy, naturally menstruating females (26 ± 3 years of age; body mass index 21.4 ± 1.9 kg/m2) were assessed during EFP and MLP ...
Yunuo Su   +3 more
wiley   +1 more source

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