Results 41 to 50 of about 17,448,991 (242)
British Journal of Clinical Pharmacology, EarlyView.SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić +7 more
wiley +1 more source
Renin-Angiotensin-Aldosterone System Antagonism and Polycystic Kidney Disease Progression. [PDF]
, 2016 Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a systemic disease characterised by the formation of multiple renal cysts that adversely affect renal function.
Chuan Kai Hian (7951946) +2 more
core +3 more sources
Journal of Pharmacological Sciences, 2010 The critical role played by the renin–angiotensin–aldosterone system (RAAS) in the regulation of blood pressure and body fluid homeostasis has been well recognized.
Akira Nishiyama, Shokei Kim-Mitsuyama
doaj +1 more source
Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
British Journal of Clinical Pharmacology, EarlyView.Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra +8 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani +15 more
wiley +1 more source
International Journal of Endocrinology, 2022 In primary hyperparathyroidism, an increased risk of developing the cardiovascular disease may exist due to increased activity of the renin-angiotensin-aldosterone system. The aim of this study was to evaluate the relationship between parathyroid hormone
Branka Milicic Stanic +5 more
doaj +1 more source
Renin-Angiotensin-Aldosterone System in Women Using Combined Oral Contraceptive: A Systematic Review
Revista Brasileira de Ginecologia e Obstetrícia, 2022 Objective To describe the effects of combined oral contraceptives (COC) on the renin-angiotensin-aldosterone system (RAAS). Data sourcesThis is a systematic review according to the criteria of Preferred Reporting Items for Systematic Reviews and Meta ...
Priscilla Araújo dos Santos +5 more
doaj +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Kaplan–Meier hypertension‐free survival by baseline body mass index category, primary adult cohort (men aged ≥ 18 years, n = 12,742). Time since baseline in years is plotted on the horizontal axis and the probability of remaining free of treated hypertension is plotted on the vertical axis. Numbers at risk are shown beneath the plot.
Ebenezer Afrifa‐Yamoah
wiley +1 more source
Вестник урологииIntroduction. Cancer provokes complex systemic responses, including perturbations of the kallikrein-kinin and renin-angiotensin-aldosterone systems.
N. D. Ushakova +8 more
doaj +1 more source